Therapeutic roles of mesenchymal stem cell-derived extracellular vesicles in cancer

Z Weng, B Zhang, C Wu, F Yu, B Han, B Li… - Journal of hematology & …, 2021 - Springer
Extracellular vesicles (EVs) are cell-derived membrane structures enclosing proteins, lipids,
RNAs, metabolites, growth factors, and cytokines. EVs have emerged as essential …

[HTML][HTML] Extracellular vesicle-based drug delivery systems for cancer treatment

S Walker, S Busatto, A Pham, M Tian, A Suh… - Theranostics, 2019 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) are naturally occurring cell-secreted nanoparticles that play
important roles in many physiological and pathological processes. EVs enable intercellular …

Injectable drug delivery systems for osteoarthritis and rheumatoid arthritis

MC Bruno, MC Cristiano, C Celia, N d'Avanzo… - ACS …, 2022 - ACS Publications
Joint diseases are one of the most common causes of morbidity and disability worldwide.
The main diseases that affect joint cartilage are osteoarthritis and rheumatoid arthritis, which …

Micro-and nanoplastics–current state of knowledge with the focus on oral uptake and toxicity

MB Paul, V Stock, J Cara-Carmona, E Lisicki… - Nanoscale …, 2020 - pubs.rsc.org
The production and use of plastics has constantly increased over the last 30 years. Over one
third of the plastics is used in disposables, which are discarded within three years of their …

The impact of nanoparticle protein corona on cytotoxicity, immunotoxicity and target drug delivery

C Corbo, R Molinaro, A Parodi… - …, 2016 - Taylor & Francis
In a perfect sequence of events, nanoparticles (NPs) are injected into the bloodstream
where they circulate until they reach the target tissue. The ligand on the NP surface …

The nanoparticle biomolecule corona: lessons learned–challenge accepted?

D Docter, D Westmeier, M Markiewicz… - Chemical Society …, 2015 - pubs.rsc.org
Besides the wide use of engineered nanomaterials (NMs) in technical products, their
applications are not only increasing in biotechnology and biomedicine, but also in the …

Safety of nanoparticles in medicine

J Wolfram, M Zhu, Y Yang, J Shen, E Gentile… - Current drug …, 2015 - ingentaconnect.com
Nanomedicine involves the use of nanoparticles for therapeutic and diagnostic purposes.
During the past two decades, a growing number of nanomedicines have received regulatory …

Nano-bio interactions in mRNA nanomedicine: Challenges and opportunities for targeted mRNA delivery

Q Saiding, Z Zhang, S Chen, F Xiao, Y Chen… - Advanced Drug Delivery …, 2023 - Elsevier
Upon entering the biological milieu, nanomedicines swiftly interact with the surrounding
tissue fluid, subsequently being enveloped by a dynamic interplay of biomacromolecules …

Clinical translation of extracellular vesicles

A Ghodasara, A Raza, J Wolfram… - Advanced …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) occur in a variety of bodily fluids and have gained recent
attraction as natural materials due to their bioactive surfaces, internal cargo, and role in …

Titania coated upconversion nanoparticles for near-infrared light triggered photodynamic therapy

SS Lucky, N Muhammad Idris, Z Li, K Huang, KC Soo… - ACS …, 2015 - ACS Publications
Because of the limited penetration depth of visible light that generally excites most of the
available photosensitizers (PSs), conventional photodynamic therapy (PDT) is limited to the …