Microglial calcium waves during the hyperacute phase of ischemic stroke

L Liu, KN Kearns, I Eli, KA Sharifi, S Soldozy… - Stroke, 2021 - Am Heart Assoc
Background and Purpose: Ischemic injury triggers multiple pathological responses in the
brain tissue, including spreading depolarizations across the cerebral cortex (cortical …

Radial, spiral and reverberating waves of spreading depolarization occur in the gyrencephalic brain

E Santos, M Schöll, R Sánchez-Porras, MA Dahlem… - Neuroimage, 2014 - Elsevier
Objectives The detection of the hemodynamic and propagation patterns of spreading
depolarizations (SDs) in the gyrencephalic brain using intrinsic optical signal imaging (IOS) …

Spreading depression: from serendipity to targeted therapy in migraine prophylaxis

C Ayata - Cephalalgia, 2009 - journals.sagepub.com
Despite the relatively well-characterized headache mechanisms in migraine, upstream
events triggering individual attacks are poorly understood. This lack of mechanistic insight …

The effect of ketamine on optical and electrical characteristics of spreading depolarizations in gyrencephalic swine cortex

R Sánchez-Porras, E Santos, M Schöll, C Stock… - …, 2014 - Elsevier
Spreading depolarization (SD) is a wave of mass neuronal and glial depolarization that
propagates across the cerebral cortex and has been implicated in the pathophysiology of …

Two-dimensional wave patterns of spreading depolarization: retracting, re-entrant, and stationary waves

MA Dahlem, R Graf, AJ Strong, JP Dreier… - Physica D: Nonlinear …, 2010 - Elsevier
We present spatio-temporal characteristics of spreading depolarizations (SD) in two
experimental systems: retracting SD wave segments observed with intrinsic optical signals …

Oxyhemoglobin and cerebral blood flow transients detect infarction in rat focal brain ischemia

J Luckl, W Baker, K Boda, M Emri, AG Yodh… - Neuroscience, 2023 - Elsevier
Spreading depolarizations (SD) refer to the near-complete depolarization of neurons that is
associated with brain injuries such as ischemic stroke. The present gold standard for SD …

Large field-of-view movement-compensated intrinsic optical signal imaging for the characterization of the haemodynamic response to spreading depolarizations in …

MJ Schöll, E Santos… - Journal of Cerebral …, 2017 - journals.sagepub.com
Haemodynamic responses to spreading depolarizations (SDs) have an important role
during the development of secondary brain damage. Characterization of the haemodynamic …

Effects of NMDA receptor antagonists with different subtype selectivities on retinal spreading depression

M Wang, PL Chazot, S Ali, SF Duckett… - British journal of …, 2012 - Wiley Online Library
BACKGROUND AND PURPOSE Spreading depression (SD) is a local, temporary disruption
of cellular ionic homeostasis that propagates slowly across the cerebral cortex and other …

Low dose isoflurane exerts opposing effects on neuronal network excitability in neocortex and hippocampus

K Becker, M Eder, A Ranft, L von Meyer… - PloS one, 2012 - journals.plos.org
The anesthetic excitement phase occurring during induction of anesthesia with volatile
anesthetics is a well-known phenomenon in clinical practice. However, the physiological …

Acute kick-boxing exercise alters effective connectivity in the brain of females with methamphetamine dependencies

L Bu, L Qi, W Yan, Q Yan, Z Tang, F Li, X Liu, C Diao… - Neuroscience …, 2020 - Elsevier
Objective Methamphetamine (METH) dependence, especially among women, is a serious
global health problem. Kick-boxing exercise can be used to reduce cue-induced craving and …