The neutrophil-to-lymphocyte and monocyte-to-lymphocyte ratios are independently associated with the severity of autoimmune encephalitis

Z Liu, Y Li, Y Wang, H Zhang, Y Lian… - Frontiers in …, 2022 - frontiersin.org
Background The neutrophil-to-lymphocyte ratio (NLR) and monocyte-to-lymphocyte ratio
(MLR) are biomarkers that may reflect inflammatory status in some immune-related …

Validation of the clinical assessment scale in autoimmune encephalitis in Chinese patients

Y Zhang, E Tu, C Yao, J Liu, Q Lei, W Lu - Frontiers in Immunology, 2021 - frontiersin.org
Background and Objectives The Clinical Assessment Scale in Autoimmune Encephalitis
(CASE) is a scale for assessing severity in autoimmune encephalitis. We aimed to validate …

Performance of the clinical assessment scale for autoimmune encephalitis in a pediatric autoimmune encephalitis cohort

H Zhou, Q Deng, Z Yang, Z Tai, K Liu, Y Ping… - Frontiers in …, 2022 - frontiersin.org
Background The Clinical Assessment Scale for Autoimmune Encephalitis (CASE), a new
scale used for rating the severity of autoimmune encephalitis (AE), has demonstrated good …

Clinical Relevance of Cerebrospinal Fluid Antibody Titers in Anti-N-Methyl-d-Aspartate Receptor Encephalitis

MT Cai, Y Zheng, S Wang, QL Lai, GL Fang, CH Shen… - Brain sciences, 2021 - mdpi.com
Anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis is the most common autoimmune
encephalitis. To date, there has been no study on the relationship between antibody (Ab) …

Impact of blood-brain barrier disruption on clinical features and treatment response in patients with newly diagnosed autoimmune encephalitis

X Cheng, Y Li, Y Wang, Y Sun, Y Lian - Journal of Neuroimmunology, 2023 - Elsevier
Aims Blood-brain barrier (BBB) breakdown is an essential mechanism in inflammatory
diseases of the central nervous system. However, the association between BBB integrity and …

Cerebrospinal fluid indices as predictors of treatment response in autoimmune encephalitis

E Popova, A Mathai, S Kannoth, P Nair… - Multiple Sclerosis and …, 2023 - Elsevier
Background Cerebrospinal fluid (CSF) indices reflecting intrathecal antibody production and
blood-brain barrier impairment are not routinely assessed in patients with autoimmune …

Simplified regimen of combined low-dose rituximab for autoimmune encephalitis with neuronal surface antibodies

Y Du, C Zhao, J Liu, C Li, Q Yan, L Li, Y Hao… - Journal of …, 2022 - Springer
Background Autoimmune encephalitis (AE) with neuronal surface antibodies (NSAbs)
presents pathogenesis mediated by B cell-secreting antibodies. Rituximab is a second-line …

Evaluation of the clinical assessment scale for autoimmune encephalitis (CASE) in a retrospective cohort and a systematic review

E Soellradl, TJ von Oertzen, JN Wagner - Neurological Sciences, 2024 - Springer
Background Autoimmune encephalitis (AE) poses significant challenges in clinical
management, requiring effective monitoring tools for therapeutic success and relapse …

Validation of the clinical assessment scale for autoimmune encephalitis in a severe autoimmune encephalitis cohort

Y He, F Li, A Yang, C Yu, Y Wang, J Zhao… - Frontiers in …, 2024 - frontiersin.org
Objective The Clinical Assessment Scale for Autoimmune Encephalitis (CASE) is a novel
tool tailored specifically for evaluating the severity of autoimmune encephalitis (AE) …

Innovation and optimization in autoimmune encephalitis trials: the design and rationale for the Phase 3, randomized study of satralizumab in patients with NMDAR-IgG …

ST Lee, H Abboud, SR Irani, H Nakajima… - Frontiers in …, 2024 - frontiersin.org
Background Autoimmune encephalitis (AIE) encompasses a spectrum of rare autoimmune-
mediated neurological disorders, which are characterized by brain inflammation and …