Background Chronic pain is defined as pain lasting beyond normal tissue healing time,
generally taken to be 12 weeks. It contributes to disability, anxiety, depression, sleep …

Despite a good outcome for many patients, approximately 20% of patients experience
chronic pain after total knee arthroplasty (TKA). Chronic pain after TKA can affect all …

Pain is considered a major clinical, social, and economic problem in communities around
the world. In this review, we describe the incidence, prevalence, and economic burden of …

The ageing revolution is changing the composition of our society with more people
becoming very old with higher risks for developing both pain and dementia. Pain is normally …

Importance Persistent pain is highly prevalent, costly, and frequently disabling in later life.
Objective To describe barriers to the management of persistent pain among older adults …

Objective To conduct a systematic review and meta-analysis to establish the association
between pain and falls in community-dwelling older adults. Data Sources Electronic …

Importance Chronic noncancer pain (hereafter referred to aschronic pain) is common among
older adults and managed frequently with pharmacotherapies that produce suboptimal …

Introduction The aim of this study was to systematically review the evidence on the
effectiveness of exercise-based telemedicine in chronic pain. Methods We searched the …

Background: A growing body of evidence suggests that neuroinflammation, which is
characterized by infiltration of immune cells, activation of mast cells and glial cells, and …

Background and aims Opioid-induced bowel dysfunction (OIBD) is an increasing problem
due to the common use of opioids for pain worldwide. It manifests with different symptoms …