Updates on liquid biopsy: Current trends and future perspectives for clinical application in solid tumors

P Pinzani, V D'Argenio, M Del Re… - Clinical Chemistry and …, 2021 - degruyter.com
Despite advances in screening and therapeutics cancer continues to be one of the major
causes of morbidity and mortality worldwide. The molecular profile of tumor is routinely …

[HTML][HTML] Diagnostic value of liquid biopsy in the era of precision medicine: 10 years of clinical evidence in cancer

V Caputo, F Ciardiello, CM Della Corte… - … of targeted anti-tumor …, 2023 - ncbi.nlm.nih.gov
Liquid biopsy is a diagnostic repeatable test, which in last years has emerged as a powerful
tool for profiling cancer genomes in real-time with minimal invasiveness and tailoring …

Precision prevention and cancer interception: the new challenges of liquid biopsy

MJ Serrano, MC Garrido-Navas, JJ Diaz Mochon… - Cancer discovery, 2020 - AACR
Despite major therapeutic progress, most advanced solid tumors are still incurable. Cancer
interception is the active way to combat cancer onset, and development of this approach …

Plasma vs. serum in circulating tumor DNA measurement: characterization by DNA fragment sizing and digital droplet polymerase chain reaction

JS Lee, M Kim, MW Seong, HS Kim, YK Lee… - Clinical Chemistry and …, 2020 - degruyter.com
Background Choosing the specimen type is the first step of the pre-analytical process.
Previous reports suggested plasma as the optimal specimen for circulating tumor DNA …

Integrity and quantity of salivary cell‐free DNA as a potential molecular biomarker in oral cancer: A preliminary study

Ó Rapado‐González, JL López‐Cedrún… - Journal of Oral …, 2022 - Wiley Online Library
Background Differences in cell‐free DNA (cfDNA) fragments have been described as a
valuable tool to distinguish cancer patients from healthy individuals. We aim to investigate …

Liquid biopsy is instrumental for 3PM dimensional solutions in cancer management

A Liskova, M Samec, L Koklesova, FA Giordano… - Journal of clinical …, 2020 - mdpi.com
One in every four deaths is due to cancer in Europe. In view of its increasing incidence,
cancer became the leading cause of death and disease burden in Denmark, France, the …

Cell free DNA as an evolving liquid biopsy biomarker for initial diagnosis and therapeutic nursing in Cancer-An evolving aspect in Medical Biotechnology

SK Ray, S Mukherjee - Current Pharmaceutical Biotechnology, 2022 - ingentaconnect.com
Cell-free DNA (cfDNA) is present in numerous body fluids and generally blood cells. It is
undoubtedly the utmost promising tool among all components of liquid biopsy. Liquid biopsy …

The utility of repetitive cell-free DNA in cancer liquid biopsies

U Gezer, AJ Bronkhorst, S Holdenrieder - Diagnostics, 2022 - mdpi.com
Liquid biopsy is a broad term that refers to the testing of body fluids for biomarkers that
correlate with a pathological condition. While a variety of body-fluid components (eg …

Targeting circulating SINEs and LINEs with DNase I provides metastases inhibition in experimental tumor models

LA Alekseeva, AV Sen'kova, MA Zenkova… - … Therapy-Nucleic Acids, 2020 - cell.com
Tumor-associated cell-free DNAs (cfDNAs) are found to play some important roles at
different stages of tumor progression; they are involved in the transformation of normal cells …

Recent advances in device engineering and computational analysis for characterization of cell-released cancer biomarkers

H Abouali, SA Hosseini, E Purcell, S Nagrath… - Cancers, 2022 - mdpi.com
Simple Summary The circulating cancer biomarkers, known as 'liquid biopsy'(LB), represent
a means to profile tumors non-invasively and collect information that can define therapeutic …