[HTML][HTML] Mechanisms and functions of multiciliary coordination

KY Wan, RN Poon - Current Opinion in Cell Biology, 2024 - Elsevier
Ciliated organisms are present in virtually every branch of the eukaryotic tree of life. In
diverse systems, cilia operate in a coordinated manner to drive fluid flows, or even propel …

Paramecium, a Model to Study Ciliary Beating and Ciliogenesis: Insights From Cutting-Edge Approaches

K Bouhouche, MS Valentine, P Le Borgne… - Frontiers in Cell and …, 2022 - frontiersin.org
Cilia are ubiquitous and highly conserved extensions that endow the cell with motility and
sensory functions. They were present in the first eukaryotes and conserved throughout …

Basal bodies bend in response to ciliary forces

AD Junker, LG Woodhams, AWJ Soh… - Molecular biology of …, 2022 - Am Soc Cell Biol
Motile cilia beat with an asymmetric waveform consisting of a power stroke that generates a
propulsive force and a recovery stroke that returns the cilium back to the start. Cilia are …

Evolutionary conservation of centriole rotational asymmetry in the human centrosome

N Gaudin, PM Gil, M Boumendjel, D Ershov… - Elife, 2022 - elifesciences.org
Centrioles are formed by microtubule triplets in a ninefold symmetric arrangement. In
flagellated protists and animal multiciliated cells, accessory structures tethered to specific …

[HTML][HTML] Centriole Translational Planar Polarity in Monociliated Epithelia

A Donati, S Schneider-Maunoury, C Vesque - Cells, 2024 - mdpi.com
Ciliated epithelia are widespread in animals and play crucial roles in many developmental
and physiological processes. Epithelia composed of multi-ciliated cells allow for directional …

cNap1 bridges centriole contact sites to maintain centrosome cohesion

R Mahen - Plos Biology, 2022 - journals.plos.org
Centrioles are non-membrane-bound organelles that participate in fundamental cellular
processes through their ability to form physical contacts with other structures. During …

Evolution of the centrosome, from the periphery to the center

J Azimzadeh - Current Opinion in Structural Biology, 2021 - Elsevier
Centrosomes are central organelles that organize microtubules (MTs) in animals, fungi and
several other eukaryotic lineages. Despite an important diversity of structure, the …

hVFL3/CCDC61 is a component of mother centriole subdistal appendages required for centrosome cohesion and positioning

V Pizon, N Gaudin, M Poteau… - Biology of the …, 2020 - Wiley Online Library
Background The centrosome regulates cell spatial organisation by controlling the
architecture of the microtubule (MT) cytoskeleton. Conversely, the position of the centrosome …

[HTML][HTML] CCDC61/VFL3 is a paralog of SAS6 and promotes ciliary functions

T Ochi, V Quarantotti, H Lin, J Jullien, IR e Silva… - Structure, 2020 - cell.com
Centrioles are cylindrical assemblies whose peripheral microtubule array displays a 9-fold
rotational symmetry that is established by the scaffolding protein SAS6. Centriole symmetry …

Coordination of cilia movements in multi-ciliated cells

M Arata, FM Usami, T Fujimori - Journal of Developmental Biology, 2022 - mdpi.com
Multiple motile cilia are formed at the apical surface of multi-ciliated cells in the epithelium of
the oviduct or the fallopian tube, the trachea, and the ventricle of the brain. Those cilia beat …