Recent applications of the Suzuki–Miyaura cross-coupling reaction in organic synthesis

S Kotha, K Lahiri, D Kashinath - Tetrahedron, 2002 - Elsevier
A general aim of transition metal-catalysed organic synthesis is carbon–carbon (C–C) bond
formation. In this respect, the Pd-catalysed Suzuki–Miyaura (SM) coupling reaction 1 is one …

Copper-catalyzed Suzuki cross-coupling using mixed nanocluster catalysts

MB Thathagar, J Beckers… - Journal of the American …, 2002 - ACS Publications
A small library of copper and noble metal nanoclusters is designed and synthesized. These
clusters are tested as catalysts in the Suzuki cross-coupling of various aryl halides with …

Review on the structures and activities of transthyretin amyloidogenesis inhibitors

X Guo, Z Liu, Y Zheng, Y Li, L Li, H Liu… - Drug design …, 2020 - Taylor & Francis
Transthyretin (TTR) is a tetrameric protein, and its dissociation, aggregation, deposition, and
misfolding are linked to several human amyloid diseases. As the main transporter for …

Polychlorinated biphenyls (PCBs) exert thyroid hormone-like effects in the fetal rat brain but do not bind to thyroid hormone receptors.

KJ Gauger, Y Kato, K Haraguchi… - Environmental …, 2004 - ehp.niehs.nih.gov
Polychlorinated biphenyls (PCBs) are ubiquitous environmental contaminants routinely
found in human and animal tissues. Developmental exposure to PCBs is associated with …

Sulfated metabolites of polychlorinated biphenyls are high-affinity ligands for the thyroid hormone transport protein transthyretin

FA Grimm, HJ Lehmler, X He… - Environmental …, 2013 - ehp.niehs.nih.gov
Background: The displacement of l-thyroxine (T4) from binding sites on transthyretin (TTR) is
considered a significant contributing mechanism in polychlorinated biphenyl (PCB)-induced …

Detection of 3, 3′-dichlorobiphenyl in human maternal plasma and its effects on axonal and dendritic growth in primary rat neurons

S Sethi, KP Keil, H Chen, K Hayakawa, X Li… - Toxicological …, 2017 - academic.oup.com
Dichlorobiphenyl (PCB 11), a byproduct of pigment production, is increasingly detected in
environmental samples. While more highly chlorinated PCB congeners are known …

Cardiovascular effects of polychlorinated biphenyls and their major metabolites

FA Grimm, WD Klaren, X Li, HJ Lehmler… - Environmental …, 2020 - ehp.niehs.nih.gov
Background: Xenobiotic metabolism is complex, and accounting for bioactivation and
detoxification processes of chemicals remains among the most challenging aspects for …

Combinatorial design of copper‐based mixed nanoclusters: New catalysts for Suzuki cross‐coupling

MB Thathagar, J Beckers… - Advanced Synthesis & …, 2003 - Wiley Online Library
Abstract Quantum dots (2–5 nm) of copper and copper/palladium mixtures are found to be
good catalysts for Suzuki cross‐coupling. The catalysts are applicable to a wide range of …

Toxicity of hydroxylated and quinoid PCB metabolites: inhibition of gap junctional intercellular communication and activation of aryl hydrocarbon and estrogen …

M Machala, L Bláha, HJ Lehmler… - Chemical research in …, 2004 - ACS Publications
In the present study, a series of 32 hydroxy-and dihydroxy-polychlorinated biphenyls (OH-
PCBs) and PCB-derived quinones were prepared and evaluated for their in vitro potencies …

Structure–Activity Relationship of Lower Chlorinated Biphenyls and Their Human-Relevant Metabolites for Astrocyte Toxicity

N Paranjape, LE Dean, A Martinez… - Chemical research in …, 2023 - ACS Publications
Exposure to polychlorinated biphenyls (PCBs) is associated with developmental
neurotoxicity and neurodegenerative disorders; however, the underlying mechanisms of …