[HTML][HTML] Current strategies for exosome cargo loading and targeting delivery

H Zeng, S Guo, X Ren, Z Wu, S Liu, X Yao - Cells, 2023 - mdpi.com
Extracellular vesicles (EVs) such as ectosomes and exosomes have gained attention as
promising natural carriers for drug delivery. Exosomes, which range from 30 to 100 nm in …

[HTML][HTML] Extracellular vesicles: a rising star for therapeutics and drug delivery

S Du, Y Guan, A Xie, Z Yan, S Gao, W Li, L Rao… - Journal of …, 2023 - Springer
Extracellular vesicles (EVs) are nano-sized, natural, cell-derived vesicles that contain the
same nucleic acids, proteins, and lipids as their source cells. Thus, they can serve as natural …

Exosomes based strategies for brain drug delivery

FU Rehman, Y Liu, M Zheng, B Shi - Biomaterials, 2023 - Elsevier
Exosome application has emerged as a promising nanotechnology discipline for various
diseases therapeutics and diagnoses. Owing to the natural properties of efficient drug …

Targeted liposomes for combined delivery of artesunate and temozolomide to resistant glioblastoma

M Ismail, W Yang, Y Li, T Chai, D Zhang, Q Du… - Biomaterials, 2022 - Elsevier
The effective treatment of glioblastoma (GBM) is a great challenge because of the blood-
brain barrier (BBB) and the growing resistance to single-agent therapeutics. Targeted …

[HTML][HTML] Nucleic acid drug vectors for diagnosis and treatment of brain diseases

ZG Lu, J Shen, J Yang, JW Wang, RC Zhao… - … and Targeted Therapy, 2023 - nature.com
Nucleic acid drugs have the advantages of rich target selection, simple in design, good and
enduring effect. They have been demonstrated to have irreplaceable superiority in brain …

Nanobiotechnology-based treatment strategies for malignant relapsed glioma

Q Qiu, X Ding, J Chen, S Chen, J Wang - Journal of Controlled Release, 2023 - Elsevier
Gliomas are the most aggressive and lethal tumors of the central nervous system, for which
few therapeutic options exist. Surgical resection is the primary treatment for most gliomas; …

[HTML][HTML] Therapeutic and diagnostic potential of exosomes as drug delivery systems in brain cancer

DI Avgoulas, KS Tasioulis, RM Papi, AA Pantazaki - Pharmaceutics, 2023 - mdpi.com
Cancer is designated as one of the principal causes of mortality universally. Among different
types of cancer, brain cancer remains the most challenging one due to its aggressiveness …

A scientometric analysis and up-to-date review of nano-based drug delivery systems in glioblastoma treatment

Y Xing, F Yasinjan, M Yang, Y Du, H Geng, M He… - Nano Today, 2023 - Elsevier
In recent years, nano-based drug delivery systems have gradually been regarded as a
promising approach to improve the current glioblastoma treatment, attracting many …

Advances in development of exosomes for ophthalmic therapeutics

Y Tian, T Zhang, J Li, Y Tao - Advanced Drug Delivery Reviews, 2023 - Elsevier
Exosomes contain multiple bioactive molecules and maintain the connection between cells.
Recent advances in exosome-based therapeutics have witnessed unprecedented …

Emerging extracellular vesicle-based carriers for glioblastoma diagnosis and therapy

J Wang, Y Liu, F Liu, S Gan, S Roy, I Hasan, B Zhang… - Nanoscale, 2023 - pubs.rsc.org
Glioblastoma (GBM) treatment is still a big clinical challenge because of its highly malignant,
invasive, and lethal characteristics. After treatment with the conventional therapeutic …