Renin-angiotensin-aldosterone (RAAS): The ubiquitous system for homeostasis and pathologies

S Patel, A Rauf, H Khan, T Abu-Izneid - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Renin-angiotensin-aldosterone system (RAAS) is a vital system of human body, as it
maintains plasma sodium concentration, arterial blood pressure and extracellular volume …

Clinical Approach to Cardiovascular Toxicity of Oral Antineoplastic Agents: JACC State-of-the-Art Review

VU Rao, DJ Reeves, AR Chugh, R O'Quinn… - Journal of the American …, 2021 - jacc.org
Precision medicine has ushered in a new era of targeted treatments for numerous
malignancies, leading to improvements in overall survival. Unlike traditional chemotherapy …

Novel insights into the treatment of SARS-CoV-2 infection: An overview of current clinical trials

F Oroojalian, A Haghbin, B Baradaran… - International Journal of …, 2020 - Elsevier
The emergence of the global pandemic caused by the novel SARS-CoV-2 virus has
motivated scientists to find a definitive treatment or a vaccine against it in the shortest …

Angiotensin receptor blockers in the management of hypertension: a real-world perspective and current recommendations

G Gallo, M Volpe, S Rubattu - Vascular Health and Risk …, 2022 - Taylor & Francis
Hypertension represents a major common cardiovascular risk factor. Optimal control of high
blood pressure levels is recommended to reduce the global burden of hypertensive …

[HTML][HTML] Clinical assessment and management of liver fibrosis in non-alcoholic fatty liver disease

A Campos-Murguía, A Ruiz-Margáin… - World journal of …, 2020 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) is among the most frequent etiologies of cirrhosis
worldwide, and it is associated with features of metabolic syndrome; the key factor …

Regulatory updates and analytical methodologies for nitrosamine impurities detection in sartans, ranitidine, nizatidine, and metformin along with sample preparation …

KM Shaik, B Sarmah, GS Wadekar… - Critical reviews in …, 2022 - Taylor & Francis
Nitrosamine impurities have been detected in various pharmaceutical products in recent
days. Various sartans, ranitidine, nizatidine, and metformin have been recalled from the …

The eye as the discrete but defensible portal of coronavirus infection

MT Coroneo - The ocular surface, 2021 - Elsevier
Oculo-centric factors may provide a key to understanding invasion success by SARS-CoV-2,
a highly contagious, potentially lethal, virus with ocular tropism. Respiratory infection …

Scaling up effective treatment of hypertension—a pathfinder for universal health coverage

TR Frieden, CV Varghese, SP Kishore… - The Journal of …, 2019 - Wiley Online Library
High blood pressure is the world's leading cause of death, but despite treatment for
hypertension being safe, effective, and low cost, most people with hypertension worldwide …

Hypertension: sex-related differences in drug treatment, prevalence and blood pressure control in primary care

JE Bager, K Manhem, T Andersson, P Hjerpe… - Journal of Human …, 2023 - nature.com
Antihypertensive treatment is equally beneficial for reducing cardiovascular risk in both men
and women. Despite this, the drug treatment, prevalence and control of hypertension differ …

Transforming growth factor-β and the renin-angiotensin system in syndromic thoracic aortic aneurysms: implications for treatment

DCH van Dorst, NP de Wagenaar… - … Drugs and Therapy, 2021 - Springer
Thoracic aortic aneurysms (TAAs) are permanent pathological dilatations of the thoracic
aorta, which can lead to life-threatening complications, such as aortic dissection and rupture …