The poor penetration of drugs into the skin (and, partially, the permeation across the stratum
corneum) often limits the efficacy of topical formulations. Basically, skin penetration can be …

Mathematical models of skin permeability play an important role in various fields including
prediction of transdermal drug delivery and assessment of dermal exposure to industrial …

Confocal Raman spectroscopy is introduced as a noninvasive in vivo optical method to
measure molecular concentration profiles in the skin. It is shown how it can be applied to …

Abstract (Trans) dermal drug therapy is gaining increasing importance in the modern drug
development. To fully utilize the potential of this route, it is important to optimize the delivery …

Mid-IR and Raman spectroscopy are versatile tools in pharmaceutics and biopharmaceutics,
with a wide field of applications ranging from characterization of drug formulations to …

This paper reviews some current methods for the in vivo assessment of local cutaneous
bioavailability in humans after topical drug application. After an introduction discussing the …

Although noninvasive, continuous monitoring of glucose concentration in blood and tissues
is one of the most challenging areas in medicine, a wide range of optical techniques has …

Topical delivery to the various regions of the skin and underlying tissues, transdermal drug
delivery and dermal exposure to environmental chemicals are important areas of research …

Due to the increased demand for reliable data regarding penetration into and permeation
across human skin, assessment of the absorption of xenobiotics has been gaining in …

In this work, the sustained bactericidal activity of chlorhexidine base loaded poly (ϵ-
caprolactone), PCL, nanocapsules against Staphylococcus epidermidis inoculated onto …