A molecular imaging primer: modalities, imaging agents, and applications

ML James, SS Gambhir - Physiological reviews, 2012 - journals.physiology.org
Molecular imaging is revolutionizing the way we study the inner workings of the human
body, diagnose diseases, approach drug design, and assess therapies. The field as a whole …

[HTML][HTML] PET/SPECT molecular imaging in clinical neuroscience: recent advances in the investigation of CNS diseases

FM Lu, Z Yuan - Quantitative imaging in medicine and surgery, 2015 - ncbi.nlm.nih.gov
Molecular imaging is an attractive technology widely used in clinical practice that greatly
enhances our understanding of the pathophysiology and treatment in central nervous …

MIRD pamphlet no. 23: quantitative SPECT for patient-specific 3-dimensional dosimetry in internal radionuclide therapy

YK Dewaraja, EC Frey, G Sgouros… - Journal of Nuclear …, 2012 - Soc Nuclear Med
In internal radionuclide therapy, a growing interest in voxel-level estimates of tissue-
absorbed dose has been driven by the desire to report radiobiologic quantities that account …

Micro-CT of rodents: state-of-the-art and future perspectives

DP Clark, CT Badea - Physica medica, 2014 - Elsevier
Micron-scale computed tomography (micro-CT) is an essential tool for phenotyping and for
elucidating diseases and their therapies. This work is focused on preclinical micro-CT …

U-SPECT-II: an ultra-high-resolution device for molecular small-animal imaging

F Van Der Have, B Vastenhouw… - Journal of Nuclear …, 2009 - Soc Nuclear Med
We present a new rodent SPECT system (U-SPECT-II) that enables molecular imaging of
murine organs down to resolutions of less than half a millimeter and high-resolution total …

Recent advances in SPECT imaging

MT Madsen - Journal of Nuclear Medicine, 2007 - Soc Nuclear Med
SPECT is a rapidly changing field, and the past several years have produced new
developments in both hardware technology and image-processing algorithms. At the …

Performance evaluation of the ECAT HRRT: an LSO-LYSO double layer high resolution, high sensitivity scanner

HWAM De Jong, FHP Van Velden… - Physics in Medicine …, 2007 - iopscience.iop.org
The ECAT high resolution research tomograph (HRRT) is a dedicated brain and small
animal PET scanner, with design features that enable high image spatial resolution …

In vivo small-animal imaging using micro-CT and digital subtraction angiography

CT Badea, M Drangova, DW Holdsworth… - Physics in medicine & …, 2008 - iopscience.iop.org
Small-animal imaging has a critical role in phenotyping, drug discovery and in providing a
basic understanding of mechanisms of disease. Translating imaging methods from humans …

Small animal SPECT and its place in the matrix of molecular imaging technologies

SR Meikle, P Kench, M Kassiou… - Physics in Medicine & …, 2005 - iopscience.iop.org
Molecular imaging refers to the use of non-invasive imaging techniques to detect signals
that originate from molecules, often in the form of an injected tracer, and observe their …

Small-animal SPECT and SPECT/CT: important tools for preclinical investigation

BL Franc, PD Acton, C Mari… - Journal of nuclear …, 2008 - Soc Nuclear Med
The need to study dynamic biologic processes in intact small-animal models of disease has
stimulated the development of high-resolution nuclear imaging methods. These methods are …