Human dendritic cell subsets: an update

M Collin, V Bigley - Immunology, 2018 - Wiley Online Library
Dendritic cells (DC) are a class of bone‐marrow‐derived cells arising from lympho‐myeloid
haematopoiesis that form an essential interface between the innate sensing of pathogens …

Human dendritic cells: their heterogeneity and clinical application potential in cancer immunotherapy

TA Patente, MP Pinho, AA Oliveira… - Frontiers in …, 2019 - frontiersin.org
Dendritic cells (DC) are professional antigen presenting cells, uniquely able to induce naïve
T cell activation and effector differentiation. They are, likewise, involved in the induction and …

CD8+ T cell activation in cancer comprises an initial activation phase in lymph nodes followed by effector differentiation within the tumor

N Prokhnevska, MA Cardenas, RM Valanparambil… - Immunity, 2023 - cell.com
Improvements in tumor immunotherapies depend on better understanding of the anti-tumor
T cell response. By studying human tumor-draining lymph nodes (TDLNs), we found that …

Transcriptional basis of mouse and human dendritic cell heterogeneity

CC Brown, H Gudjonson, Y Pritykin, D Deep… - Cell, 2019 - cell.com
Dendritic cells (DCs) play a critical role in orchestrating adaptive immune responses due to
their unique ability to initiate T cell responses and direct their differentiation into effector …

[HTML][HTML] Transcriptional and functional analysis of CD1c+ human dendritic cells identifies a CD163+ subset priming CD8+ CD103+ T cells

P Bourdely, G Anselmi, K Vaivode, RN Ramos… - Immunity, 2020 - cell.com
Dendritic cells (DCs) are antigen-presenting cells controlling T cell activation. In humans, the
diversity, ontogeny, and functional capabilities of DC subsets are not fully understood. Here …

[HTML][HTML] NK cells stimulate recruitment of cDC1 into the tumor microenvironment promoting cancer immune control

JP Böttcher, E Bonavita, P Chakravarty, H Blees… - Cell, 2018 - cell.com
Conventional type 1 dendritic cells (cDC1) are critical for antitumor immunity, and their
abundance within tumors is associated with immune-mediated rejection and the success of …

Guidelines for the use of flow cytometry and cell sorting in immunological studies

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2019 - Wiley Online Library
These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

The role of dendritic cells in cancer and anti-tumor immunity

AE Marciscano, N Anandasabapathy - Seminars in immunology, 2021 - Elsevier
Dendritic cells (DC) are key sentinels of the host immune response with an important role in
linking innate and adaptive immunity and maintaining tolerance. There is increasing …

Dendritic cell subsets and locations

S Balan, M Saxena, N Bhardwaj - International review of cell and molecular …, 2019 - Elsevier
Dendritic cells (DCs) are a unique class of immune cells that act as a bridge between innate
and adaptive immunity. The discovery of DCs by Cohen and Steinman in 1973 laid the …

Homeostatic IL-13 in healthy skin directs dendritic cell differentiation to promote TH2 and inhibit TH17 cell polarization

JU Mayer, KL Hilligan, JS Chandler, DA Eccles… - Nature …, 2021 - nature.com
The signals driving the adaptation of type 2 dendritic cells (DC2s) to diverse peripheral
environments remain mostly undefined. We show that differentiation of CD11blo migratory …