The injured spinal cord is difficult to repair and regenerate. Traditional treatments are not
effective. Stem cells are a type of cells that have the potential to differentiate into various …

Multiple sclerosis is a complex autoimmune disorder which characterized by demyelination
and axonal loss in the central nervous system (CNS). Several evidences indicate that some …

Burn injuries have been reported to be an important cause of morbidity and mortality and
they are still considered as unmet clinical need. Although there is a myriad of effective stem …

In this study, we present a novel chitosan-intercalated montmorillonite/poly (vinyl
alcohol)(OMMT/PVA) nanofibrous mesh as a microenvironment for guiding differentiation of …

Objective Spermatogonial stem cells (SSCs) provide the cellular basis for sperm production
transforming the male's genetic information to the next generation. We aimed to examine the …

Regenerative medicine has been shown to hold enormous potential to treat traumatic and
degenerative diseases, and substantial advancements have been made in the recent …

Transplantation of embryonic stem cells (ESCs) is a promising therapeutic approach for the
treatment of neurodegenerative diseases. However, ESCs are not usable clinically due to …

Background Recent progress in the induced generation of dopaminergic (DA) neurons from
different types of stem cells or reprogrammed somatic cells holds tremendous potential for …

Methods: Human Dental Pulp Stem Cells (hDPSCs) are noninvasive, autologous and easy
available source with multipotency characteristics, so they are in focus of interest in …

Mimicking the microenvironment of seminiferous tubules plays an indispensable role in
directing differentiation of stem cells toward germ cells in vitro. In this work, we fabricated …