Dengue virus infection elicits highly polarized CX3CR1+ cytotoxic CD4+ T cells associated with protective immunity
Dengue virus (DENV) is a rapidly spreading pathogen with unusual pathogenesis, and
correlates of protection from severe dengue disease and vaccine efficacy have not yet been …
correlates of protection from severe dengue disease and vaccine efficacy have not yet been …
Host genetics and dengue fever
C Xavier-Carvalho, CC Cardoso… - Infection, Genetics and …, 2017 - Elsevier
Dengue is a major worldwide problem in tropical and subtropical areas; it is caused by four
different viral serotypes, and it can manifest as asymptomatic, mild, or severe. Many factors …
different viral serotypes, and it can manifest as asymptomatic, mild, or severe. Many factors …
Can non-human primates serve as models for investigating dengue disease pathogenesis?
KB Clark, N Onlamoon, HM Hsiao, GC Perng… - Frontiers in …, 2013 - frontiersin.org
Dengue Virus (DV) infects between 50 and 100 million people globally, with public health
costs totaling in the billions. It is the causative agent of dengue fever (DF) and dengue …
costs totaling in the billions. It is the causative agent of dengue fever (DF) and dengue …
SB203580 modulates p38 MAPK signaling and dengue virus-induced liver injury by reducing MAPKAPK2, HSP27, and ATF2 phosphorylation
GP Sreekanth, A Chuncharunee, A Sirimontaporn… - PloS one, 2016 - journals.plos.org
Dengue virus (DENV) infection causes organ injuries, and the liver is one of the most
important sites of DENV infection, where viral replication generates a high viral load. The …
important sites of DENV infection, where viral replication generates a high viral load. The …
[HTML][HTML] Increased expression of cytokines, soluble cytokine receptors, soluble apoptosis ligand and apoptosis in dengue
J Arias, N Valero, J Mosquera, M Montiel, E Reyes… - Virology, 2014 - Elsevier
Several studies have been performed to determine biomarkers that define the risk factors to
developing severe forms of dengue. In this study, the levels of TNF-α, IL-6, IL-1, IL-17 …
developing severe forms of dengue. In this study, the levels of TNF-α, IL-6, IL-1, IL-17 …
Single nucleotide polymorphisms in candidate genes and dengue severity in children: A case–control, functional and meta-analysis study
C Xavier-Carvalho, G Gibson, P Brasil… - Infection, Genetics and …, 2013 - Elsevier
Dengue is an arthropod-borne emerging viral disease with high morbidity and mortality risk
in tropical countries like Brazil. Clinical manifestations are vast, ranging from asymptomatic …
in tropical countries like Brazil. Clinical manifestations are vast, ranging from asymptomatic …
Identification of genetic variants associated with dengue or West Nile virus disease: a systematic review and meta-analysis
ME Cahill, S Conley, AT DeWan… - BMC infectious diseases, 2018 - Springer
Abstract Background Dengue and West Nile viruses are highly cross-reactive and have
numerous parallels in geography, potential vector host (Aedes family of mosquitoes), and …
numerous parallels in geography, potential vector host (Aedes family of mosquitoes), and …
Meta-analysis of the relationship between TNF-α (− 308G/A) and IL-10 (− 819C/T) gene polymorphisms and susceptibility to dengue
ACM Santos, EL de Moura, JM Ferreira… - Immunological …, 2017 - Taylor & Francis
Objective: This study determined whether tumor necrosis factor alpha (TNF-α) and
Interleukin-10 (IL-10) polymorphisms are associated with susceptibility to dengue. Methods …
Interleukin-10 (IL-10) polymorphisms are associated with susceptibility to dengue. Methods …
Association of promoter region polymorphisms of CD209 gene with clinical outcomes of dengue virus infection in Western India
K Alagarasu, IM Damle, RV Bachal, AP Mulay… - Infection, Genetics and …, 2013 - Elsevier
Dendritic cell specific intercellular adhesion molecule 3 grabbing non-integrin, coded by the
CD209 gene, acts as an entry receptor for dengue virus. Polymorphisms in the promoter …
CD209 gene, acts as an entry receptor for dengue virus. Polymorphisms in the promoter …
Association of combinations of interleukin-10 and pro-inflammatory cytokine gene polymorphisms with dengue hemorrhagic fever
K Alagarasu, RV Bachal, H Tillu, AP Mulay, MB Kakade… - Cytokine, 2015 - Elsevier
Pro-inflammatory and anti-inflammatory cytokines have been shown to play an important
role in dengue disease pathogenesis. In the present study, to find out whether single …
role in dengue disease pathogenesis. In the present study, to find out whether single …