Bioconjugation methodologies have proven to play a central enabling role in the recent
development of biotherapeutics and chemical biology approaches. Recent endeavours in …

Protein semisynthesis—defined herein as the assembly of a protein from a combination of
synthetic and recombinant fragments—is a burgeoning field of chemical biology that has …

Applications for advanced functional soft materials that possess precisely engineered
properties and functional groups have been expanding significantly with the development of …

Liposomal delivery systems have significantly enhanced the efficacy and safety of
chemotherapeutic agents compared to free (non-liposomal) formulations. Liposomes are …

The maleimide motif is widely used for the selective chemical modification of cysteine
residues in proteins. Despite widespread utilization, there are some potential limitations …

The bioconjugation of proteins—that is, the creation of a covalent link between a protein and
any other molecule—has been studied for decades, partly because of the numerous …

Bioconjugation via azide– Staudinger ligation : an overview - Chemical Society Reviews (RSC
Publishing) DOI:10.1039/C0CS00123F Royal Society of Chemistry View PDF VersionPrevious …

A quantitative structure− reactivity relationship for the Michael-type addition of thiols onto
acrylates was determined. Several thiol-containing peptides were investigated by examining …

Hydrogels are used in a wide variety of biomedical applications including tissue
engineering, biomolecule delivery, cell delivery, and cell culture. These hydrogels are often …

Chemoselective ligation reactions have contributed immensely to the development of
organic synthesis and chemical biology. However, the ligation of stoichiometric amounts of …