Oxidative stress (OS) arises when the body is subjected to harmful endogenous or
exogenous factors that overwhelm the antioxidant system. There is increasing evidence that …

Purpose This paper reviews marine compounds that target the mitogen-activated protein
kinase (MAPK) signaling pathway and their main sources, chemical structures, major …

The mitochondrion is a very versatile organelle that participates in some important cancer‐
associated biological processes, including energy metabolism, oxidative stress …

Mitochondria are the target sites for multiple disease manifestations, for which it is appealing
to researchers' attention for advanced pharmacological interventions. Mitochondrial …

Mitochondria are vital organelles found within living cells and have signalling, biosynthetic,
and bioenergetic functions. Mitochondria play a crucial role in metabolic reprogramming …

Microorganisms are regarded as a sustainable source of biologically active molecules.
Among them, Trichoderma spp. have been an attractive source of biological compounds …

Endophytic fungi produce a range of known metabolites and several others, not yet
explored, which present important biological activities from the pharmaceutical and …

Osteosarcoma is a malignant, life-threatening tumor that affects children and adolescents. In
this study, we identified high levels of calponin 3 (CNN3) protein in osteosarcoma tissues …

Ovarian cancer has a high mortality rate and high resistance to chemotherapy. Thus, many
studies are currently assessing the ability of natural products to induce ovarian cancer cell …

A new α-pyrone analog, arthrifuranone A (1) was isolated from an EtOAc-extract of
Arthrinium pseudosinense culture medium. The isolation workflow was guided by a …