Characteristic effect of hydroxyurea on the higher-order structure of DNA and gene expression
H Ogawa, T Nishio, Y Yoshikawa, K Sadakane… - Scientific Reports, 2024 - nature.com
Hydroxyurea (HU; hydroxycarbamide) is a chemotherapy medication used to treat various
types of cancer and other diseases such as sickle cell anemia. HU inhibits DNA synthesis by …
types of cancer and other diseases such as sickle cell anemia. HU inhibits DNA synthesis by …
Chlorogenic Acid Protects DNA against Double-strand Breaks: Evidence from Single Molecule Observation
H Ogawa, T Nishio, Y Yoshikawa, K Sadakane… - Chemistry …, 2023 - academic.oup.com
A natural polyphenol chlorogenic acid (CGA) is regarded as an antioxidant by preventing
oxidative damage. Among the oxidative damages, DNA double-strand breaks (DSBs) are …
oxidative damage. Among the oxidative damages, DNA double-strand breaks (DSBs) are …