This review aims at juxtaposing common versus distinct structural and functional strategies
that are applied by aptamers, riboswitches, and ribozymes/DNAzymes. Focusing on recently …

The computational study of enantioselective reactions is a challenging task that requires
high accuracy, as very small energy differences have to be reproduced. Quantum chemical …

DNAzymes have become attractive due to their potential biomedical and biotechnological
applications, as well as their advantages in terms of stability, efficiency and synthetic …

The Kukhtin–Ramirez reaction of 2-(3-oxo-3-phenyl) ethoxy-benzo [d]-1, 3, 2-
dioxaphospholes with perfluorodiacetyl was monitored by NMR methods. To our surprise …

The first reported reaction mechanism of a DNAzyme, ie 9DB1, by using molecular dynamics
(MD) simulations includes some ambiguities. We try to overcome some of these ambiguous …

Deoxyribozymes (DNAzymes) are small, synthetic, single-stranded DNAs capable of
catalyzing chemical reactions, including RNA ligation. Herein, we report a novel class of …

A copper‐dependent self‐cleaving DNA (DNAzyme or deoyxyribozyme) previously isolated
by in vitro selection has been analyzed by a combination of Molecular Dynamics (MD) …

The reaction of hexafluoroacetone with 5, 5-dimethyl-2-(2-oxo-1, 2-diphenylethoxy)-1, 3, 2-
dioxaphosphorinane occurs in two simultaneous directions: through the formation of cage …

A synthetic DNA enzyme catalyses the formation of a native phosphodiester bond between
two RNA fragments, but the molecular details of the mechanism remained elusive. Research …

Catalytic (ZnCl 2, Et 3 N) phosphorylation of tert-butylacetylacetone with 2-chloro-1, 3, 2-
benzodioxaphosphole unexpectedly occurs with elimination of proton from the methyl group …