Immunology of Mycobacterium tuberculosis Infections

JK Sia, J Rengarajan - Microbiology spectrum, 2019 - Am Soc Microbiol
Tuberculosis (TB) is a serious global public health challenge that results in significant
morbidity and mortality worldwide. TB is caused by infection with the bacilli Mycobacterium …

Feed, microbiota, and gut immunity: using the zebrafish model to understand fish health

A López Nadal, W Ikeda-Ohtsubo, D Sipkema… - Frontiers in …, 2020 - frontiersin.org
Aquafeed companies aim to provide solutions to the various challenges related to nutrition
and health in aquaculture. Solutions to promote feed efficiency and growth, as well as …

CARD9+ microglia promote antifungal immunity via IL-1β- and CXCL1-mediated neutrophil recruitment

RA Drummond, M Swamydas, V Oikonomou… - Nature …, 2019 - nature.com
The C-type lectin receptor–Syk (spleen tyrosine kinase) adaptor CARD9 facilitates protective
antifungal immunity within the central nervous system (CNS), as human deficiency in …

Zebrafish regulatory T cells mediate organ-specific regenerative programs

SP Hui, DZ Sheng, K Sugimoto, A Gonzalez-Rajal… - Developmental cell, 2017 - cell.com
The attenuation of ancestral pro-regenerative pathways may explain why humans do not
efficiently regenerate damaged organs. Vertebrate lineages that exhibit robust regeneration …

Metformin modulates innate immune-mediated inflammation and early progression of NAFLD-associated hepatocellular carcinoma in zebrafish

S de Oliveira, RA Houseright, AL Graves… - Journal of …, 2019 - Elsevier
Background & Aims Non-alcoholic fatty liver disease/non-alcoholic steatohepatitis
(NAFLD/NASH) is an increasing clinical problem associated with progression to …

Under pressure: interactions between commensal microbiota and the teleost immune system

C Kelly, I Salinas - Frontiers in immunology, 2017 - frontiersin.org
Commensal microorganisms inhabit every mucosal surface of teleost fish. At these surfaces,
microorganisms directly and indirectly shape the teleost immune system. This review …

Immunity of the intestinal mucosa in teleost fish

M Stosik, B Tokarz-Deptuła, W Deptuła - Fish & Shellfish Immunology, 2023 - Elsevier
The paper presents the problem of intestinal mucosa immunity in teleost fish. The immunity
of the intestinal mucosa in teleost fish depends on the elements and mechanisms with …

Single-cell RNA-sequencing uncovers transcriptional states and fate decisions in haematopoiesis

EI Athanasiadis, JG Botthof, H Andres, L Ferreira… - Nature …, 2017 - nature.com
The success of marker-based approaches for dissecting haematopoiesis in mouse and
human is reliant on the presence of well-defined cell surface markers specific for diverse …

Gut immune system and the implications of oral-administered immunoprophylaxis in finfish aquaculture

PT Lee, FY Yamamoto, CF Low, JY Loh… - Frontiers in …, 2021 - frontiersin.org
The gastrointestinal immune system plays an important role in immune homeostasis
regulation. It regulates the symbiotic host-microbiome interactions by training and …

Single-cell analyses reveal early thymic progenitors and pre-B cells in zebrafish

SA Rubin, CS Baron, C Pessoa Rodrigues… - Journal of Experimental …, 2022 - rupress.org
The zebrafish has proven to be a valuable model organism for studying hematopoiesis, but
relatively little is known about zebrafish immune cell development and functional diversity …