In vitro models for thrombogenicity testing of blood-recirculating medical devices

DN Sarode, S Roy - Expert review of medical devices, 2019 - Taylor & Francis
Introduction: Blood-recirculating medical devices, such as mechanical circulatory support
(MCS), extracorporeal membrane oxygenators (ECMO), and hemodialyzers, are commonly …

Rotary mechanical circulatory support systems

M Hosseinipour, R Gupta, M Bonnell… - … of Rehabilitation and …, 2017 - journals.sagepub.com
A detailed survey of the current trends and recent advances in rotary mechanical circulatory
support systems is presented in this paper. Rather than clinical reports, the focus is on …

A predictive model of high shear thrombus growth

M Mehrabadi, LDC Casa, CK Aidun, DN Ku - Annals of Biomedical …, 2016 - Springer
The ability to predict the timescale of thrombotic occlusion in stenotic vessels may improve
patient risk assessment for thrombotic events. In blood contacting devices, thrombosis …

Computational fluid dynamics-based design optimization for an implantable miniature Maglev pediatric ventricular assist device

J Wu, JF Antaki, J Verkaik, S Snyder, M Ricci - 2012 - asmedigitalcollection.asme.org
Computational fluid dynamics (CFD)-based design optimization was applied to achieve the
finalized design of the PediaFlow® PF4, a magnetically levitated rotodynamic pediatric …

Performance analysis of a miniature turbine generator for intracorporeal energy harvesting

A Pfenniger, R Vogel, VM Koch, M Jonsson - Artificial organs, 2014 - Wiley Online Library
Replacement intervals of implantable medical devices are commonly dictated by battery life.
Therefore, intracorporeal energy harvesting has the potential to reduce the number of …

Cardiac assist with a twist: apical torsion as a means to improve failing heart function

DR Trumble, WE McGregor, RCP Kerckhoffs… - 2011 - asmedigitalcollection.asme.org
Changes in muscle fiber orientation across the wall of the left ventricle (LV) cause the apex
of the heart to turn 10–15 deg in opposition to its base during systole and are believed to …

Design optimization of a wearable artificial pump-lung device with computational modeling

M Ertan Taskin, T Zhang, KH Fraser, BP Griffith… - 2012 - asmedigitalcollection.asme.org
The heart-lung machine has commonly been used to replace the functions of both the heart
and lungs during open heart surgeries or implemented as extracorporeal membrane …

Multiobjective Optimization of Rotodynamic Blood Pumps: The Use Case of a Cavopulmonary Assist Device

A Escher, S Miric, B Thamsen, R Giuffrida… - ASAIO …, 2024 - journals.lww.com
Comprehensive optimization of rotodynamic blood pumps (RBPs) requires the consideration
of three partially conflicting objectives: size, hemocompatibility, and motor efficiency …

In Vitro and In Vivo Performance Evaluation of the Second Developmental Version of the PediaFlow Pediatric Ventricular Assist Device

TM Maul, E Kocyildirim, CA Johnson, AR Daly… - Cardiovascular …, 2011 - Springer
Ventricular assist devices (VADs) have significantly impacted the treatment of adult cardiac
failure, but few options exist for pediatric patients. This has motivated our group to develop …

Toward the development of the PediaFlow™ pediatric ventricular assist device: Past, present, future

HS Borovetz, SE Olia, JF Antaki - Applications in Engineering Science, 2022 - Elsevier
Abstract Ventricular Assist Devices (VADs) have revolutionized treatment of adult heart
failure with tens of thousands of devices implanted either as a “bridge” to transplant or as a …