Bacterial motility: machinery and mechanisms

N Wadhwa, HC Berg - Nature reviews microbiology, 2022 - nature.com
Bacteria have developed a large array of motility mechanisms to exploit available resources
and environments. These mechanisms can be broadly classified into swimming in aqueous …

Type IV Pili: dynamic bacterial nanomachines

CK Ellison, GB Whitfield, YV Brun - FEMS Microbiology Reviews, 2022 - academic.oup.com
Bacteria and archaea rely on appendages called type IV pili (T4P) to participate in diverse
behaviors including surface sensing, biofilm formation, virulence, protein secretion and …

Globally distributed Myxococcota with photosynthesis gene clusters illuminate the origin and evolution of a potentially chimeric lifestyle

L Li, D Huang, Y Hu, NM Rudling, DP Canniffe… - Nature …, 2023 - nature.com
Photosynthesis is a fundamental biogeochemical process, thought to be restricted to a few
bacterial and eukaryotic phyla. However, understanding the origin and evolution of …

[HTML][HTML] Discovery of bioactive microbial gene products in inflammatory bowel disease

Y Zhang, A Bhosle, S Bae, LJ McIver, G Pishchany… - Nature, 2022 - nature.com
Microbial communities and their associated bioactive compounds,–are often disrupted in
conditions such as the inflammatory bowel diseases (IBD). However, even in well …

Unmasking of the von Willebrand A-domain surface adhesin CglB at bacterial focal adhesions mediates myxobacterial gliding motility

ST Islam, NY Jolivet, C Cuzin, AM Belgrave, L My… - Science …, 2023 - science.org
The predatory deltaproteobacterium Myxococcus xanthus uses a helically-trafficked motor at
bacterial focal-adhesion (bFA) sites to power gliding motility. Using total internal reflection …

Synthetic peptides that form nanostructured micelles have potent antibiotic and antibiofilm activity against polymicrobial infections

S Chou, H Guo, FG Zingl, S Zhang… - Proceedings of the …, 2023 - National Acad Sciences
The emergence of multidrug-resistant bacterial pathogens is a growing threat to global
public health. Here, we report the development and characterization of a panel of nine …

Bdellovibrio predation cycle characterized at nanometre-scale resolution with cryo-electron tomography

M Kaplan, YW Chang, CM Oikonomou, WJ Nicolas… - Nature …, 2023 - nature.com
Bdellovibrio bacteriovorus is a microbial predator that offers promise as a living antibiotic for
its ability to kill Gram-negative bacteria, including human pathogens. Even after six decades …

The structure and mechanism of the bacterial type II secretion system

S Naskar, M Hohl, M Tassinari… - Molecular …, 2021 - Wiley Online Library
The type II secretion system (T2SS) is a multi‐protein complex used by many bacteria to
move substrates across their cell membrane. Substrates released into the environment …

The power of touch: type 4 pili, the von Willebrand a domain, and surface sensing by Pseudomonas aeruginosa

SS Webster, GCL Wong, GA O'Toole - Journal of Bacteriology, 2022 - Am Soc Microbiol
Most microbes in the biosphere are attached to surfaces, where they experience mechanical
forces due to hydrodynamic flow and cell-to-substratum interactions. These forces likely …

A cell surface-exposed protein complex with an essential virulence function in Ustilago maydis

N Ludwig, S Reissmann, K Schipper, C Gonzalez… - Nature …, 2021 - nature.com
Plant pathogenic fungi colonizing living plant tissue secrete a cocktail of effector proteins to
suppress plant immunity and reprogramme host cells. Although many of these effectors …