Alzheimer's disease (AD) is the most prevalent form of dementia, with complex
pathophysiology that is not fully understood. While β‐amyloid plaque and neurofibrillary …

Dexmedetomidin is a new-generation, highly selective α2 adrenergic receptor agonist with a
large number of advantages, including its sedative and analgesic properties, its ability to …

Head trauma is the most common cause of disability in young adults. Known as a silent
epidemic, it can cause a mosaic of symptoms, whether neurological (sensory–motor …

Repeated mild traumatic brain injury (rmTBI) poses adversity in the form of neurological
deficits. The ignition of long-term neurological aberrations post-TBI is appended with the …

The past decade has witnessed unprecedented medical progress, which has translated into
cardiac surgery being increasingly common and safe. However, complications such as …

Background: Neuroprotective effects of dexmedetomidine are reported in preclinical and
clinical studies but evidence regarding the postoperative neurocognitive function is still …

Dexmedetomidine (DEX) is a highly selective α2 receptor agonist that is routinely used in
the clinic for sedation and anesthesia. Recently, an increasing number of studies have …

Circular RNAs (circRNAs) have a regulatory function on inflammation and autophagy, of
which rno-circRNA_010705 (circLrp1b) appears to be significantly up-regulated following …

Dexmedetomidine, a highly selective α2-adrenoceptor agonist, has sedative, anxiolytic,
analgesic, sympatholytic, and opioid-sparing properties and induces a unique sedative …

Over the past few years, despite the lack of approved pediatric labelling, dexmedetomidine's
(DEX) use has become more prevalent in pediatric clinical practice as well as in research …