Mesenchymal stem cell derived-exosomes: a modern approach in translational medicine

S Nikfarjam, J Rezaie, NM Zolbanin, R Jafari - Journal of translational …, 2020 - Springer
Mesenchymal stem cells (MSCs) have captured great attention in regenerative medicine for
over a few decades by virtue of their differentiation capacity, potent immunomodulatory …

[HTML][HTML] Progress, opportunity, and perspective on exosome isolation-efforts for efficient exosome-based theranostics

D Yang, W Zhang, H Zhang, F Zhang, L Chen, L Ma… - Theranostics, 2020 - ncbi.nlm.nih.gov
Exosomes are small extracellular vesicles with diameters of 30-150 nm. In both
physiological and pathological conditions, nearly all types of cells can release exosomes …

Recent advancements in the use of exosomes as drug delivery systems

EJ Bunggulawa, W Wang, T Yin, N Wang… - Journal of …, 2018 - Springer
Extracellular vesicles (EVs) are the substances that are released by most types of cells and
have an important role in cell to cell communication. Among the most highly researched EVs …

Extracellular vesicle isolation methods: rising impact of size-exclusion chromatography

M Monguió-Tortajada, C Gálvez-Montón… - Cellular and Molecular …, 2019 - Springer
Extracellular vesicles (EVs) include a variety of nanosized vesicles released to the
extracellular microenvironment by the vast majority of cells transferring bioactive lipids …

[PDF][PDF] Liver macrophages: old dogmas and new insights

A Guillot, F Tacke - Hepatology communications, 2019 - Wiley Online Library
Inflammation is a hallmark of virtually all liver diseases, such as liver cancer, fibrosis,
nonalcoholic steatohepatitis, alcoholic liver disease, and cholangiopathies. Liver …

A comparison of traditional and novel methods for the separation of exosomes from human samples

LL Yu, J Zhu, JX Liu, F Jiang, WK Ni… - BioMed research …, 2018 - Wiley Online Library
Exosomes are discrete populations of small (40‐200 nm in diameter) membranous vesicles
that are released into the extracellular space by most cell types, eventually accumulating in …

Extracellular vesicles as circulating cancer biomarkers: opportunities and challenges

RE Lane, D Korbie, MM Hill, M Trau - Clinical and translational medicine, 2018 - Springer
Extracellular vesicles (EVs) are small, lipid-bound particles containing nucleic acid and
protein cargo which are excreted from cells under a variety of normal and pathological …

Improved isolation strategies to increase the yield and purity of human urinary exosomes for biomarker discovery

AH Gheinani, M Vögeli, U Baumgartner, E Vassella… - Scientific reports, 2018 - nature.com
Circulating miRNAs are detected in extracellular space and body fluids such as urine.
Circulating RNAs can be packaged in secreted urinary extracellular vesicles (uEVs) and …

[HTML][HTML] Commonly used methods for extracellular vesicles' enrichment: Implications in downstream analyses and use

M Clos-Sansalvador, M Monguió-Tortajada… - European Journal of …, 2022 - Elsevier
Extracellular vesicles (EVs) are becoming promising tools for clinical application, either as
sources of disease-specific molecular signatures for the unraveling of disease …

Eliciting anti-cancer immunity by genetically engineered multifunctional exosomes

Q Cheng, Z Dai, G Smbatyan, AL Epstein, HJ Lenz… - Molecular Therapy, 2022 - cell.com
Exosomes are cell-derived nanovesicles involved in regulating intercellular
communications. In contrast to conventional nanomedicines, exosomes are characterized by …