Emerging potential of 5-Fluorouracil-loaded chitosan nanoparticles in cancer therapy

TT Dongsar, TS Dongsar, N Gupta, WH Almalki… - Journal of Drug Delivery …, 2023 - Elsevier
Cancer is among the leading causes of mortality in the globe. Chemotherapy utilizing
various anticancer medicines continues to be the most widely used form of treatment …

Amelioration of cancer employing chitosan, its derivatives, and chitosan-based nanoparticles: recent updates

T Virmani, G Kumar, A Sharma, K Pathak, MS Akhtar… - Polymers, 2023 - mdpi.com
The limitations associated with the conventional treatment of cancer have necessitated the
design and development of novel drug delivery systems based mainly on nanotechnology …

Potential of curcumin and niacin-loaded targeted chitosan coated liposomes to activate autophagy in hepatocellular carcinoma cells: An in vitro evaluation in HePG2 …

NAN Hanafy, RF Sheashaa, EA Moussa… - International journal of …, 2023 - Elsevier
The objective of this study is to activate autophagy in hepatocellular carcinoma for the
enhancement of its cellular degradation. Liposomes incorporated chitosan in the core used …

Current advances in chitosan nanoparticles based oral drug delivery for colorectal cancer treatment

H Choukaife, S Seyam, B Alallam… - International journal …, 2022 - Taylor & Francis
As per the WHO, colorectal cancer (CRC) caused around 935,173 deaths worldwide in 2020
in both sexes and at all ages. The available anticancer therapies including chemotherapy …

Chitosan nanoparticles and based composites as a biocompatible vehicle for drug delivery: a review

R Pathak, S Bhatt, VD Punetha, M Punetha - International Journal of …, 2023 - Elsevier
The shellfish processing industry is one of the largest growing industries across the globe
with a market size of around USD 62B. However, it also leads to a significant environmental …

Carbohydrate polymers-based surface modified nano delivery systems for enhanced target delivery to colon cancer-A review

IAA Ibrahim, AR Alzahrani, IM Alanazi… - International Journal of …, 2023 - Elsevier
Carbohydrate polymers-based surface-modified nano-delivery systems have gained
significant attention in recent years for enhancing targeted delivery to colon cancer. These …

Enhanced delivery of doxorubicin for breast cancer treatment using pH-sensitive starch/PVA/g-C3N4 hydrogel

P Alipournazari, M Pourmadadi, M Abdouss… - International Journal of …, 2024 - Elsevier
This study introduces a starch/PVA/gC 3 N 4 nanocarrier hydrogel for pH-sensitive DOX
delivery in breast cancer. DOX was loaded into the nanocarrier with 44.75% loading …

Synthesis, characterization and in vitro digestion of folate conjugated chitosan-loaded proanthocyanidins nanoparticles

Z Ding, W Chen, F Jiang, M Mo, Y Bi, F Kong - Food Research International, 2023 - Elsevier
Proanthocyanidins have significant biological activity and pharmacological effects and are
widely used in food, medicine, and cosmetics. Chitosan nanoparticles loaded with …

Advances in chitosan-based drug delivery systems: A comprehensive review for therapeutic applications

A Haider, S Khan, DN Iqbal, M Shrahili, S Haider… - European Polymer …, 2024 - Elsevier
Chitosan (CS), a biocompatible and biodegradable polymer produced from chitin, has
attracted interest in drug delivery due to its unique properties and diverse applications. Over …

Surface-modified biobased polymeric nanoparticles for dual delivery of doxorubicin and gefitinib in glioma cell lines

M Farheen, MH Akhter, H Chitme, M Suliman… - ACS …, 2023 - ACS Publications
Glioma is a malignant form of brain cancer that is challenging to treat due to the progressive
growth of glial cells. To target overexpressed folate receptors in glioma brain tumors, we …