Nongenomic actions of thyroid hormone

PJ Davis, F Goglia, JL Leonard - Nature Reviews Endocrinology, 2016 - nature.com
The nongenomic actions of thyroid hormone begin at receptors in the plasma membrane,
mitochondria or cytoplasm. These receptors can share structural homologies with nuclear …

Molecular aspects of thyroid hormone actions

SY Cheng, JL Leonard, PJ Davis - Endocrine reviews, 2010 - academic.oup.com
Cellular actions of thyroid hormone may be initiated within the cell nucleus, at the plasma
membrane, in cytoplasm, and at the mitochondrion. Thyroid hormone nuclear receptors …

Overview of nomenclature of nuclear receptors

P Germain, B Staels, C Dacquet, M Spedding… - Pharmacological …, 2006 - ASPET
Nuclear receptor pharmacology has, to a certain extent, led the way, compared with other
receptor systems, in the appreciation that ligands may exert very diverse pharmacology …

Thyroid hormones as modulators of immune activities at the cellular level

P De Vito, S Incerpi, JZ Pedersen, P Luly, FB Davis… - Thyroid, 2011 - liebertpub.com
Background: Increasing evidence suggests that thyroid hormones, L-thyroxine (T4) and 3,
3′, 5-triiodo-L-thyronine (T3), are modulators of the immune response. In monocytes …

Thyroid hormone: sex-dependent role in nervous system regulation and disease

S Baksi, A Pradhan - Biology of sex differences, 2021 - Springer
Thyroid hormone (TH) regulates many functions including metabolism, cell differentiation,
and nervous system development. Alteration of thyroid hormone level in the body can lead …

Role of thyroid hormone in skeletal muscle physiology

FF Bloise, A Cordeiro… - Journal of …, 2018 - joe.bioscientifica.com
Thyroid hormones (TH) are crucial for development, growth, differentiation, metabolism and
thermogenesis. Skeletal muscle (SM) contractile function, myogenesis and bioenergetic …

Integrin αVβ3 Contains a Cell Surface Receptor Site for Thyroid Hormone that Is Linked to Activation of Mitogen-Activated Protein Kinase and Induction of …

JJ Bergh, HY Lin, L Lansing, SN Mohamed… - …, 2005 - academic.oup.com
Integrin αVβ3 is a heterodimeric plasma membrane protein whose several extracellular
matrix protein ligands contain an RGD recognition sequence. This study identifies integrin …

Mechanisms of nongenomic actions of thyroid hormone

PJ Davis, JL Leonard, FB Davis - Frontiers in neuroendocrinology, 2008 - Elsevier
The nongenomic actions of thyroid hormone require a plasma membrane receptor or
nuclear receptors located in cytoplasm. The plasma membrane receptor is located on …

Membrane receptor for thyroid hormone: physiologic and pharmacologic implications

PJ Davis, FB Davis, SA Mousa… - Annual review of …, 2011 - annualreviews.org
Plasma membrane integrin αvβ3 is a cell surface receptor for thyroid hormone at which
nongenomic actions are initiated. L-thyroxine (T4) and 3, 3′, 5-triiodo-L-thyronine (T3) …

Genomic and non-genomic mechanisms of action of thyroid hormones and their catabolite 3, 5-diiodo-l-thyronine in mammals

M Giammanco, CM Di Liegro, G Schiera… - International Journal of …, 2020 - mdpi.com
Since the realization that the cellular homologs of a gene found in the retrovirus that
contributes to erythroblastosis in birds (v-erbA), ie the proto-oncogene c-erbA encodes the …