[HTML][HTML] Pathophysiological mechanisms and therapeutic approaches in obstructive sleep apnea syndrome

R Lv, X Liu, Y Zhang, N Dong, X Wang, Y He… - Signal transduction and …, 2023 - nature.com
Obstructive sleep apnea syndrome (OSAS) is a common breathing disorder in sleep in
which the airways narrow or collapse during sleep, causing obstructive sleep apnea. The …

[HTML][HTML] Obstructive sleep apnea and inflammation: proof of concept based on two illustrative cytokines

L Kheirandish-Gozal, D Gozal - International journal of molecular …, 2019 - mdpi.com
Obstructive sleep apnea syndrome (OSAS) is a markedly prevalent condition across the
lifespan, particularly in overweight and obese individuals, which has been associated with …

[HTML][HTML] Molecular pathology, oxidative stress, and biomarkers in obstructive sleep apnea

PG Meliante, F Zoccali, F Cascone… - International Journal of …, 2023 - mdpi.com
Obstructive sleep apnea syndrome (OSAS) is characterized by intermittent hypoxia (IH)
during sleep due to recurrent upper airway obstruction. The derived oxidative stress (OS) …

[HTML][HTML] miR-223: an effective regulator of immune cell differentiation and inflammation

P Jiao, XP Wang, ZM Luoreng, J Yang… - … Journal of Biological …, 2021 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) play a critical role in regulating various biological processes, such as
cell differentiation and immune modulation by binding to their target genes. miR-223 is a …

Research progress on the role of exosomes in obstructive sleep apnea-hypopnea syndrome-related atherosclerosis

P Cai, Y Zheng, Y Zhou, M Li, YC Shi, H Lin… - Sleep Medicine …, 2022 - Elsevier
Cardiovascular disease (CVD) is a leading cause of mortality worldwide. Atherosclerosis, a
multifactorial disease with complicated pathogenesis, is the main cause of CVD, underlying …

[HTML][HTML] MicroRNAs and obesity-induced endothelial dysfunction: key paradigms in molecular therapy

K Ait-Aissa, QM Nguyen, M Gabani, A Kassan… - Cardiovascular …, 2020 - Springer
The endothelium plays a pivotal role in maintaining vascular health. Obesity is a global
epidemic that has seen dramatic increases in both adult and pediatric populations. Obesity …

Impact of obstructive sleep apnea in cardiovascular risk in the pediatric population: A systematic review

M Castillo-García, E Solano-Pérez, C Coso… - Sleep Medicine …, 2023 - Elsevier
While the association of obstructive sleep apnea (OSA) with an increased cardiovascular
risk (CVR) in the adult population is well known, there is insufficient evidence to affirm …

[HTML][HTML] Circulating exosomes and gut microbiome induced insulin resistance in mice exposed to intermittent hypoxia: Effects of physical activity

A Khalyfa, A Ericsson, Z Qiao, I Almendros, R Farré… - …, 2021 - thelancet.com
Background Gut microbiota (GM) contribute to obesity and insulin resistance (IR).
Obstructive sleep apnea (OSA), characterized by intermittent hypoxia (IH), promotes IR and …

[HTML][HTML] Cardiac fibroblasts and cardiac fibrosis: precise role of exosomes

P Ranjan, R Kumari, SK Verma - Frontiers in cell and developmental …, 2019 - frontiersin.org
Exosomes are a group of extracellular microvesicles that deliver biologically active RNAs,
proteins, lipids and other signaling molecules to recipient cells. Classically, exosomes act as …

The clinical potential of adipogenesis and obesity-related microRNAs

M Zaiou, H El Amri, A Bakillah - Nutrition, Metabolism and Cardiovascular …, 2018 - Elsevier
Obesity is a growing health problem commonly associated with numerous metabolic
disorders including type 2 diabetes, hypertension, cardiovascular disease, and some forms …