Diabetes mellitus predisposes affected individuals to a significant spectrum of
cardiovascular complications, one of the most debilitating in terms of prognosis is heart …

Background: Diastolic dysfunction (DD) is associated with the development of heart failure
and contributes to the pathogenesis of other cardiac maladies, including atrial fibrillation …

Metabolic diseases are considered the primary culprit for physical and mental health of
individuals. Although the diagnosis of these diseases is relatively easy, more effective and …

In the present study, we aimed to evaluate the effect of Sirt1, Sirt3 and combined activation
in high fructose diet-induced insulin resistance rat heart and assessed the cardiac function …

Dapagliflozin (DAPA), a sodium–glucose cotransporter 2 inhibitor, is approved for
treatments of patients with diabetes. The DAPA-HF (Dapagliflozin and Prevention of Adverse …

Type 2 diabetes mellitus (T2DM) undermines health and quality of life (QoL). This cross-
sectional study surveyed 138 consenting T2DM patients from North-Eastern Romania with …

Background Diabetic peripheral neuropathy (DPN) is the most prevalent complication of
diabetes, and has been demonstrated to be independently associated with cardiovascular …

Introduction Quercetin (Que) is a potent anti-inflammatory and antioxidant flavonoid with
cardioprotective potential. However, very little is known about the signaling pathways and …

Background: This study aimed to explore whether 99m Tc-radiolabeled fibroblast activation
protein inhibitor (99m Tc-HFAPi) imaging can detect early myocardial fibrosis in the …

Background Fluid overload is common in patients with diabetes and chronic kidney disease
(DM and CKD; DMCKD) and can lead to structural and functional cardiac abnormalities …