Structure, function, and immunomodulation of the CD8 co-receptor
S Srinivasan, C Zhu, AC McShan - Frontiers in Immunology, 2024 - frontiersin.org
Expressed on the surface of CD8+ T cells, the CD8 co-receptor is a key component of the T
cells that contributes to antigen recognition, immune cell maturation, and immune cell …
cells that contributes to antigen recognition, immune cell maturation, and immune cell …
Integrating experiment and theory to understand TCR-pMHC dynamics
The conformational dynamism of proteins is well established. Rather than having a single
structure, proteins are more accurately described as a conformational ensemble that exists …
structure, proteins are more accurately described as a conformational ensemble that exists …
[HTML][HTML] The crystal structure of the MHC class I (MHC-I) molecule in the green anole lizard demonstrates the unique MHC-I system in reptiles
Y Wang, Z Qu, L Ma, X Wei, N Zhang… - The Journal of …, 2021 - journals.aai.org
The reptile MHC class I (MCH-I) and MHC class II proteins are the key molecules in the
immune system; however, their structure has not been investigated. The crystal structure of …
immune system; however, their structure has not been investigated. The crystal structure of …
Discovery and analysis of invertebrate IgVJ-C2 structure from amphioxus provides insight into the evolution of the Ig superfamily
R Chen, L Zhang, J Qi, N Zhang, L Zhang… - The Journal of …, 2018 - journals.aai.org
The emergence of adaptive immunity in jawed vertebrates depended on the appearance of
variable immune receptors, BCRs and TCRs, which exhibit variable-J–constant (V JC)–type …
variable immune receptors, BCRs and TCRs, which exhibit variable-J–constant (V JC)–type …
Protodomains: symmetry-related supersecondary structures in proteins and self-complementarity
P Youkharibache - Protein Supersecondary Structures: Methods and …, 2019 - Springer
We will consider in this chapter supersecondary structures (SSS) as a set of secondary
structure elements (SSEs) found in protein domains. Some SSS arrangements/topologies …
structure elements (SSEs) found in protein domains. Some SSS arrangements/topologies …
The first crystal structure of CD8αα from a cartilaginous fish
Introduction Cartilaginous fishes are the most evolutionary-distant vertebrates from
mammals and possess an immunoglobulin (Ig)-and T cell-mediated adaptive immunity. CD8 …
mammals and possess an immunoglobulin (Ig)-and T cell-mediated adaptive immunity. CD8 …
The combination of CD8αα and peptide-MHC-I in a face-to-face mode promotes chicken γδT cells response
Y Liu, R Chen, R Liang, B Sun, Y Wu, L Zhang… - Frontiers in …, 2020 - frontiersin.org
The CD8αα homodimer is crucial to both thymic T cell selection and the antigen recognition
of cytotoxic T cells. The CD8-pMHC-I interaction can enhance CTL immunity via stabilizing …
of cytotoxic T cells. The CD8-pMHC-I interaction can enhance CTL immunity via stabilizing …
Structural insights into the evolution feature of a bony fish CD8αα homodimer
J Wang, N Zhang, Z Wang, W Yanan, L Zhang… - Molecular immunology, 2018 - Elsevier
The CD8αα homodimer structures of endotherms demonstrate that despite distinct diversity
at the amino acid sequence level, a few conserved key amino acids ensure common …
at the amino acid sequence level, a few conserved key amino acids ensure common …
Analisis Molekular dan Transpor Ion Amonium Clorida
G Rhaska, R Zainul - 2019 - osf.io
Ammonium Chlorida merupakan seanyawa anorganik dengan rumus kimia NH4Cl, berupa
garam Kristal putih yang sangat mudah larut dalam air. Ammonium Chlorida banyak …
garam Kristal putih yang sangat mudah larut dalam air. Ammonium Chlorida banyak …
Avian T cells: antigen recognition and lineages
AL Smith, TW Göbel - Avian immunology, 2022 - Elsevier
The T cell receptor/CD3 complex is crucial for antigen recognition and signal transduction by
T lymphocytes. Here we discuss the general features of the chicken TCR/CD3 complex …
T lymphocytes. Here we discuss the general features of the chicken TCR/CD3 complex …