Production of bioactive plant secondary metabolites through in vitro technologies—status and outlook
C Wawrosch, SB Zotchev - Applied Microbiology and Biotechnology, 2021 - Springer
Medicinal plants have been used by mankind since ancient times, and many bioactive plant
secondary metabolites are applied nowadays both directly as drugs, and as raw materials …
secondary metabolites are applied nowadays both directly as drugs, and as raw materials …
Next-generation metabolic engineering approaches towards development of plant cell suspension cultures as specialized metabolite producing biofactories
Plant cell suspension culture (PCSC) has emerged as a viable technology to produce plant
specialized metabolites (PSM). While Taxol® and ginsenoside are two examples of …
specialized metabolites (PSM). While Taxol® and ginsenoside are two examples of …
A hybrid model based on general regression neural network and fruit fly optimization algorithm for forecasting and optimizing paclitaxel biosynthesis in Corylus …
Background Paclitaxel is a well-known chemotherapeutic agent widely applied as a therapy
for various types of cancers. In vitro culture of Corylus avellana has been named as a …
for various types of cancers. In vitro culture of Corylus avellana has been named as a …
Natural rubber-producing sources, systems, and perspectives for breeding and biotechnology studies of Taraxacum kok-saghyz
Abstract Natural rubber (NR, cis-1, 4-polyisoprene) is applied in over 50,000 products. It has
unique properties, which cannot be matched by synthetic rubber. The pará rubber tree …
unique properties, which cannot be matched by synthetic rubber. The pará rubber tree …
[HTML][HTML] Exploring the role of elicitors in enhancing medicinal values of plants under in vitro condition
Plants have been scrutinized as the great repository of various natural compounds referred
to as secondary metabolites. Secondary metabolites possess diverse organic effects that …
to as secondary metabolites. Secondary metabolites possess diverse organic effects that …
Mathematical Modeling of Growth and Paclitaxel Biosynthesis in Corylus avellana Cell Culture Responding to Fungal Elicitors Using Multilayer Perceptron-Genetic …
Paclitaxel is the top-selling anticancer medicine in the world. In vitro culture of Corylus
avellana has been made known as a promising and inexpensive strategy for producing …
avellana has been made known as a promising and inexpensive strategy for producing …
Biotechnology and in vitro culture as an alternative system for secondary metabolite production
M Mohaddab, Y El Goumi, M Gallo, D Montesano… - Molecules, 2022 - mdpi.com
Medicinal plants are rich sources of bioactive compounds widely used as medicaments,
food additives, perfumes, and agrochemicals. These secondary compounds are produced …
food additives, perfumes, and agrochemicals. These secondary compounds are produced …
Research advances in clinical applications, anticancer mechanism, total chemical synthesis, semi-synthesis and biosynthesis of paclitaxel
S Zhang, T Ye, Y Liu, G Hou, Q Wang, F Zhao, F Li… - Molecules, 2023 - mdpi.com
Paclitaxel, a natural secondary metabolite isolated and purified from the bark of the Taxus
tree, is considered one of the most successful natural anticancer drugs due to its low toxicity …
tree, is considered one of the most successful natural anticancer drugs due to its low toxicity …
Modeling of paclitaxel biosynthesis elicitation in Corylus avellana cell culture using adaptive neuro-fuzzy inference system-genetic algorithm (ANFIS-GA) and multiple …
Paclitaxel as a microtubule-stabilizing agent is widely used for the treatment of a vast range
of cancers. Corylus avellana cell suspension culture (CSC) is a promising strategy for …
of cancers. Corylus avellana cell suspension culture (CSC) is a promising strategy for …
Whole fungal elicitors boost paclitaxel biosynthesis induction in Corylus avellana cell culture
Paclitaxel is an effective natural-source chemotherapeutic agent commonly applied to treat a
vast range of cancers. In vitro Corylus avellana culture has been reported as a promising …
vast range of cancers. In vitro Corylus avellana culture has been reported as a promising …