Chronic kidney disease (CKD) is a long-term condition in which the kidneys do not work
correctly. It has a high prevalence and represents a serious hazard to human health and …

The COVID‐19 pandemic caused by the severe acute respiratory syndrome coronavirus 2
(SARS‐CoV‐2) has overwhelmed healthcare systems requiring the rapid development of …

Renal interstitial fibrosis: mechanisms and evaluation : Current Opinion in Nephrology and
Hypertension Renal interstitial fibrosis: mechanisms and evaluation : Current Opinion in …

Objective—Oxidative stress is considered a hallmark of atherosclerosis. In particular, the
superoxide-generating type 1 NADPH oxidase (NOX1) has been shown to be induced and …

Fabry disease is a rare X-linked hereditary disease caused by mutations in the AGAL gene
encoding the lysosomal enzyme alpha-galactosidase A. Enzyme replacement therapy (ERT) …

Cancer patients receiving anthracycline-based chemotherapy are at risk to develop life-
threatening chronic cardiotoxicity with the pathophysiological mechanism of action not fully …

Arterial growth and remodeling at the tissue level is driven by mechanobiological processes
at cellular and sub-cellular levels. Although it is widely accepted that cells seek to promote …

3‐hydroxy‐3‐methylglutaryl coenzyme A reductase inhibitors (statins) have been variably
noted to affect hepatitis C virus (HCV) treatment response, fibrosis progression, and …

Fibrosis is a pathological repair process common among organs, that responds to tissue
damage by replacement with non-functional connective tissue. Despite the widespread …

Tuberculosis (TB) is a lethal disease and remains one of the top ten causes of mortality by
an infectious disease worldwide. It can also result in significant morbidity related to …