[PDF][PDF] Cytotoxic T cells and viral hepatitis.
FV Chisari - The Journal of clinical investigation, 1997 - Am Soc Clin Investig
The hepatitis B (HBV) 1 and C (HCV) viruses are noncytopathic, hepatotropic viruses that
cause acute and chronic hepatitis and hepatocellular carcinoma (1). The cellular immune …
cause acute and chronic hepatitis and hepatocellular carcinoma (1). The cellular immune …
[PDF][PDF] Pathogenesis of chronic hepatitis C: immunological features of hepatic injury and viral persistence
A Cerny, FV Chisari - Hepatology, 1999 - Wiley Online Library
The immune response to viral antigens is thought to be responsible for viral clearance and
disease pathogenesis during hepatitis C virus (HCV) infection. In chronically infected …
disease pathogenesis during hepatitis C virus (HCV) infection. In chronically infected …
Determinants of viral clearance and persistence during acute hepatitis C virus infection
R Thimme, D Oldach, KM Chang, C Steiger… - The Journal of …, 2001 - rupress.org
The virological and immunological features of hepatitis C virus (HCV) infection were studied
weekly for 6 months after accidental needlestick exposure in five health care workers, four of …
weekly for 6 months after accidental needlestick exposure in five health care workers, four of …
Analysis of successful immune responses in persons infected with hepatitis C virus
F Lechner, DKH Wong, PR Dunbar… - The Journal of …, 2000 - rupress.org
Although hepatitis C virus (HCV) infection is very common, identification of patients during
acute infection is rare. Consequently, little is known about the immune response during this …
acute infection is rare. Consequently, little is known about the immune response during this …
Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease
R Thimme, J Bukh, HC Spangenberg… - Proceedings of the …, 2002 - National Acad Sciences
To define the early events that determine the outcome of acute hepatitis C virus (HCV)
infection, we compared the course of viremia with the peripheral and intrahepatic T cell …
infection, we compared the course of viremia with the peripheral and intrahepatic T cell …
[HTML][HTML] Analysis of a successful immune response against hepatitis C virus
S Cooper, AL Erickson, EJ Adams, J Kansopon… - Immunity, 1999 - cell.com
To investigate the type of immunity responsible for resolution of hepatitis C virus (HCV)
infection, we monitored antibody and intrahepatic cytotoxic T lymphocyte (CTL) responses …
infection, we monitored antibody and intrahepatic cytotoxic T lymphocyte (CTL) responses …
Cellular immune responses persist and humoral responses decrease two decades after recovery from a single-source outbreak of hepatitis C
A Takaki, M Wiese, G Maertens, E Depla, U Seifert… - Nature medicine, 2000 - nature.com
As acute hepatitis C virus (HCV) infection is clinically inapparent in most cases, the
immunologic correlates of recovery are not well defined. The cellular immune response is …
immunologic correlates of recovery are not well defined. The cellular immune response is …
Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection
H Wedemeyer, XS He, M Nascimbeni… - The Journal of …, 2002 - journals.aai.org
The cellular immune response contributes to clearance of hepatitis C virus (HCV) and
persists for decades after recovery from infection. The immunological basis for the …
persists for decades after recovery from infection. The immunological basis for the …
Sustained Dysfunction of Antiviral CD8+ T Lymphocytes after Infection with Hepatitis C Virus
NH Gruener, F Lechner, MC Jung, H Diepolder… - Journal of …, 2001 - Am Soc Microbiol
Hepatitis C virus (HCV) sets up persistent infection in the majority of those exposed. It is
likely that, as with other persistent viral infections, the efficacy of T-lymphocyte responses …
likely that, as with other persistent viral infections, the efficacy of T-lymphocyte responses …
Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection.
HM Diepolder, R Zachoval, RM Hoffmann… - Lancet (London …, 1995 - europepmc.org
In acute hepatitis C virus (HCV) infection only 20-50% of patients spontaneously clear the
virus. To characterise the immune reaction during that phase we studied the response of …
virus. To characterise the immune reaction during that phase we studied the response of …