Small RNAs, spermatogenesis, and male infertility: a decade of retrospect

M Joshi, S Sethi, P Mehta, A Kumari… - Reproductive Biology and …, 2023 - Springer
Small non-coding RNAs (sncRNAs), being the top regulators of gene expression, have been
thoroughly studied in various biological systems, including the testis. Research over the last …

Small non-coding RNAs in male reproduction

O Olotu, A Ahmedani, N Kotaja - Seminars in Reproductive …, 2024 - thieme-connect.com
Male reproductive functions are strictly regulated in order to maintain sperm production and
fertility. All processes are controlled by precise regulation of gene expression, which creates …

MIWI N-terminal RG motif promotes efficient pachytene piRNA production and spermatogenesis independent of LINE1 transposon silencing

C Wei, J Jing, X Yan, JM Mann, R Geng, H Xie… - PLoS …, 2023 - journals.plos.org
PIWI proteins and their associated piRNAs act to silence transposons and promote
gametogenesis. Murine PIWI proteins MIWI, MILI, and MIWI2 have multiple arginine and …

Small noncoding RNAs and sperm nuclear basic proteins reflect the environmental impact on germ cells

G Ferrero, R Festa, L Follia, G Lettieri, S Tarallo… - Molecular …, 2024 - Springer
Background Molecular techniques can complement conventional spermiogram analyses to
provide new information on the fertilizing potential of spermatozoa and to identify early …

[HTML][HTML] Comprehensive analyses of 435 goat transcriptomes provides insight into male reproduction

H Xu, S Zhang, Q Duan, M Lou, Y Ling - International Journal of Biological …, 2024 - Elsevier
A systematic analysis of genes related to reproduction is crucial for obtaining a
comprehensive understanding of the molecular mechanisms that underlie male reproductive …

[HTML][HTML] Mechanisms Behind the Impact of PIWI Proteins on Cancer Cells: Literature Review

P Limanówka, B Ochman… - International Journal of …, 2024 - mdpi.com
The P-Element-induced wimpy testis (PIWI) group of proteins plays a key role in RNA
interference, particularly in the regulation of small non-coding RNAs. However, in recent …

[HTML][HTML] piRNA array analysis provide insight into the mechanism of DEHP-induced testicular toxicology in pubertal male rats

G Fu, Q Wu, J Dai, S Lu, T Zhou, Z Yang… - … and Environmental Safety, 2024 - Elsevier
Abstract Di-(2-ethylhexyl) phthalate (DEHP), a widely used plasticizer, could cause male
reproductive toxicity by disrupting spermatogenesis. Piwi-interacting RNAs (piRNAs) are a …

Phenotypic continuum and poor intracytoplasmic sperm injection intracytoplasmic sperm injection prognosis in patients harboring HENMT1 variants

Z Wehbe, A Barbotin, A Boursier, C Cazin… - …, 2024 - Wiley Online Library
Abstract Background Small RNAs interacting with PIWI (piRNAs) play a crucial role in
regulating transposable elements and translation during spermatogenesis and are essential …

Epigenetics of nonobstructive azoospermia

S Gunes, AM Mahmutoglu, N Hekim - Asian Journal of Andrology, 2024 - journals.lww.com
Nonobstructive azoospermia (NOA) is a severe and heterogeneous form of male factor
infertility caused by dysfunction of spermatogenesis. Although various factors are well …

A novel nonsense mutation of PNLDC1 associated with male infertility due to oligo-astheno-teratozoospermia in a consanguineous Chinese family

Q Fang, X Bi, H Wei, S Liu, J Di, Y Liu… - QJM: An International …, 2023 - academic.oup.com
novel nonsense mutation of PNLDC1 associated with male infertility due to oligo-astheno-teratozoospermia
in a consanguineous Chinese family | QJM: An International Journal of Medicine | Oxford …