Cellular mechanisms of tissue fibrosis. 4. Structural and functional consequences of skeletal muscle fibrosis

RL Lieber, SR Ward - American Journal of Physiology-Cell …, 2013 - journals.physiology.org
Skeletal muscle fibrosis can be a devastating clinical problem that arises from many causes,
including primary skeletal muscle tissue diseases, as seen in the muscular dystrophies, or it …

The role of animal models in tendon research

MW Hast, A Zuskov, LJ Soslowsky - Bone & joint research, 2014 - boneandjoint.org.uk
Tendinopathy is a debilitating musculoskeletal condition which can cause significant pain
and lead to complete rupture of the tendon, which often requires surgical repair. Due in part …

Age-and level-dependence of fatty infiltration in lumbar paravertebral muscles of healthy volunteers

RJ Crawford, L Filli, JM Elliott, D Nanz… - American Journal …, 2016 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Normative age-related decline in paravertebral muscle
quality is important for reference to disease and risk identification in patients. We aimed to …

Manually defining regions of interest when quantifying paravertebral muscles fatty infiltration from axial magnetic resonance imaging: a proposed method for the …

RJ Crawford, J Cornwall, R Abbott, JM Elliott - BMC musculoskeletal …, 2017 - Springer
Background There is increasing interest in paravertebral muscle composition as a potential
prognostic and diagnostic element in lumbar spine health. As a consequence, it is becoming …

MRI-defined paraspinal muscle morphology in Japanese population: The Wakayama Spine Study

T Sasaki, N Yoshimura, H Hashizume, H Yamada… - PloS one, 2017 - journals.plos.org
Objective This study aimed to establish sex-and age-dependent distributions of the cross
sectional area and fatty infiltration ratio of paraspinal muscles, and to examine the …

Muscle–fat MRI: 1.5 tesla and 3.0 tesla versus histology

AC Smith, TB Parrish, R Abbott, MA Hoggarth… - Muscle & …, 2014 - Wiley Online Library
Introduction: We evaluated muscle/fat fraction (MFF) accuracy and reliability measured with
an MR imaging technique at 1.5 Tesla (T) and 3.0 T scanner strengths, using biopsy as …

A mouse model of delayed rotator cuff repair results in persistent muscle atrophy and fatty infiltration

Z Wang, X Liu, MR Davies, D Horne… - … American journal of …, 2018 - journals.sagepub.com
Background: Rotator cuff (RC) tears are common tendon injuries seen in orthopaedic
patients. Successful repair of large and massive RC tears remains a challenge due to our …

PPARγ controls ectopic adipogenesis and cross-talks with myogenesis during skeletal muscle regeneration

G Dammone, S Karaz, L Lukjanenko, C Winkler… - International journal of …, 2018 - mdpi.com
Skeletal muscle is a regenerative tissue which can repair damaged myofibers through the
activation of tissue-resident muscle stem cells (MuSCs). Many muscle diseases with …

Upregulation of transforming growth factor-β signaling in a rat model of rotator cuff tears

X Liu, SK Joshi, B Ravishankar, D Laron, HT Kim… - Journal of shoulder and …, 2014 - Elsevier
Background Muscle atrophy, fatty infiltration, and fibrosis of the muscle have been described
as important factors governing outcome after rotator cuff injury and repair. Muscle fibrosis is …

Ultrasound assessment of deep cervical extensors morphology and quality in populations with whiplash associated disorders: An intra-and inter-examiner reliability …

JA Valera-Calero, C Fernández-de-Las-Peñas… - … Science and Practice, 2022 - Elsevier
Background Ultrasound imaging (US) has shown to be a reliable and valid tool for
assessing muscle morphology and quality. However, most studies have focused on …