[HTML][HTML] Prediction of drug–ABC-transporter interaction—Recent advances and future challenges
F Montanari, GF Ecker - Advanced drug delivery reviews, 2015 - Elsevier
With the discovery of P-glycoprotein (P-gp), it became evident that ABC-transporters play a
vital role in bioavailability and toxicity of drugs. They prevent intracellular accumulation of …
vital role in bioavailability and toxicity of drugs. They prevent intracellular accumulation of …
Streaming the web: Reasoning over dynamic data
In the last few years a new research area, called stream reasoning, emerged to bridge the
gap between reasoning and stream processing. While current reasoning approaches are …
gap between reasoning and stream processing. While current reasoning approaches are …
The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY
SD Harding, JL Sharman, E Faccenda… - Nucleic acids …, 2018 - academic.oup.com
Abstract The IUPHAR/BPS Guide to PHARMACOLOGY (GtoPdb, www.
guidetopharmacology. org) and its precursor IUPHAR-DB, have captured expert-curated …
guidetopharmacology. org) and its precursor IUPHAR-DB, have captured expert-curated …
DisGeNET: a discovery platform for the dynamical exploration of human diseases and their genes
DisGeNET is a comprehensive discovery platform designed to address a variety of
questions concerning the genetic underpinning of human diseases. DisGeNET contains …
questions concerning the genetic underpinning of human diseases. DisGeNET contains …
Building event-centric knowledge graphs from news
Abstract Knowledge graphs have gained increasing popularity in the past couple of years,
thanks to their adoption in everyday search engines. Typically, they consist of fairly static …
thanks to their adoption in everyday search engines. Typically, they consist of fairly static …
A simple standard for sharing ontological mappings (SSSOM)
Despite progress in the development of standards for describing and exchanging scientific
information, the lack of easy-to-use standards for mapping between different representations …
information, the lack of easy-to-use standards for mapping between different representations …
Chemometrics and cheminformatics in the analysis of biologically active peptides from food sources
A Iwaniak, P Minkiewicz, M Darewicz… - Journal of Functional …, 2015 - Elsevier
Bioactive peptides are often studied by applying computer analysis prior to in vitro and in
vivo protocols. This has been made possible by progresses in the development of new …
vivo protocols. This has been made possible by progresses in the development of new …
DisGeNET-RDF: harnessing the innovative power of the Semantic Web to explore the genetic basis of diseases
Motivation: DisGeNET-RDF makes available knowledge on the genetic basis of human
diseases in the Semantic Web. Gene-disease associations (GDAs) and their provenance …
diseases in the Semantic Web. Gene-disease associations (GDAs) and their provenance …
API-centric linked data integration: The open PHACTS discovery platform case study
Data integration is a key challenge faced in pharmacology where there are numerous
heterogeneous databases spanning multiple domains (eg chemistry and biology). To …
heterogeneous databases spanning multiple domains (eg chemistry and biology). To …
A new wave of innovation in Semantic web tools for drug discovery
Introduction: The use of semantic web technologies to aid drug discovery has gained
momentum over recent years. Researchers in this domain have realized that semantic web …
momentum over recent years. Researchers in this domain have realized that semantic web …