[HTML][HTML] Prediction of drug–ABC-transporter interaction—Recent advances and future challenges

F Montanari, GF Ecker - Advanced drug delivery reviews, 2015 - Elsevier
With the discovery of P-glycoprotein (P-gp), it became evident that ABC-transporters play a
vital role in bioavailability and toxicity of drugs. They prevent intracellular accumulation of …

Streaming the web: Reasoning over dynamic data

A Margara, J Urbani, F Van Harmelen, H Bal - Journal of Web Semantics, 2014 - Elsevier
In the last few years a new research area, called stream reasoning, emerged to bridge the
gap between reasoning and stream processing. While current reasoning approaches are …

The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY

SD Harding, JL Sharman, E Faccenda… - Nucleic acids …, 2018 - academic.oup.com
Abstract The IUPHAR/BPS Guide to PHARMACOLOGY (GtoPdb, www.
guidetopharmacology. org) and its precursor IUPHAR-DB, have captured expert-curated …

DisGeNET: a discovery platform for the dynamical exploration of human diseases and their genes

J Piñero, N Queralt-Rosinach, A Bravo, J Deu-Pons… - Database, 2015 - academic.oup.com
DisGeNET is a comprehensive discovery platform designed to address a variety of
questions concerning the genetic underpinning of human diseases. DisGeNET contains …

Building event-centric knowledge graphs from news

M Rospocher, M Van Erp, P Vossen, A Fokkens… - Journal of Web …, 2016 - Elsevier
Abstract Knowledge graphs have gained increasing popularity in the past couple of years,
thanks to their adoption in everyday search engines. Typically, they consist of fairly static …

A simple standard for sharing ontological mappings (SSSOM)

N Matentzoglu, JP Balhoff, SM Bello, C Bizon… - Database, 2022 - academic.oup.com
Despite progress in the development of standards for describing and exchanging scientific
information, the lack of easy-to-use standards for mapping between different representations …

Chemometrics and cheminformatics in the analysis of biologically active peptides from food sources

A Iwaniak, P Minkiewicz, M Darewicz… - Journal of Functional …, 2015 - Elsevier
Bioactive peptides are often studied by applying computer analysis prior to in vitro and in
vivo protocols. This has been made possible by progresses in the development of new …

DisGeNET-RDF: harnessing the innovative power of the Semantic Web to explore the genetic basis of diseases

N Queralt-Rosinach, J Pinero, À Bravo, F Sanz… - …, 2016 - academic.oup.com
Motivation: DisGeNET-RDF makes available knowledge on the genetic basis of human
diseases in the Semantic Web. Gene-disease associations (GDAs) and their provenance …

API-centric linked data integration: The open PHACTS discovery platform case study

P Groth, A Loizou, AJG Gray, C Goble, L Harland… - Journal of web …, 2014 - Elsevier
Data integration is a key challenge faced in pharmacology where there are numerous
heterogeneous databases spanning multiple domains (eg chemistry and biology). To …

A new wave of innovation in Semantic web tools for drug discovery

S Kanza, JG Frey - Expert Opinion on Drug Discovery, 2019 - Taylor & Francis
Introduction: The use of semantic web technologies to aid drug discovery has gained
momentum over recent years. Researchers in this domain have realized that semantic web …