Machine learning strategies in microRNA research: bridging genome to phenome

S Daniel Thomas, K Vijayakumar, L John… - OMICS: A Journal of …, 2024 - liebertpub.com
MicroRNAs (miRNAs) have emerged as a prominent layer of regulation of gene expression.
This article offers the salient and current aspects of machine learning (ML) tools and …

[HTML][HTML] The long non-coding RNA NEAT1 promotes the progression of human ovarian cancer through targeting miR-214-3p and regulating angiogenesis

Y Liu, Y Li, Y Wu, Y Zhao, X Hu, C Sun - Journal of Ovarian Research, 2023 - Springer
Background Angiogenesis and metastasis contributes substantially to the poor outcome of
patients with ovarian cancer. We aimed to explore the role and mechanisms of the long non …

[HTML][HTML] Computational prediction of new therapeutic effects of probiotics

S Sulaimany, K Farahmandi, A Mafakheri - Scientific Reports, 2024 - nature.com
Probiotics are living microorganisms that provide health benefits to their hosts, potentially
aiding in the treatment or prevention of various diseases, including diarrhea, irritable bowel …

SEBGLMA: Semantic Embedded Bipartite Graph Network for Predicting lncRNA‐miRNA Associations

ZY Zhao, J Lin, Z Wang, JX Guo… - … Journal of Intelligent …, 2023 - Wiley Online Library
Identifying the association between long noncoding RNA (lncRNA) and micro‐RNA (miRNA)
is of great significance for the treatment of diseases by interfering with the combination of …

[HTML][HTML] SVMMDR: Prediction of miRNAs-drug resistance using support vector machines based on heterogeneous network

T Duan, Z Kuang, L Deng - Frontiers in Oncology, 2022 - frontiersin.org
In recent years, the miRNA is considered as a potential high-value therapeutic target
because of its complex and delicate mechanism of gene regulation. The abnormal …

[HTML][HTML] Inferring pseudogene–MiRNA associations based on an ensemble learning framework with similarity kernel fusion

C Fan, M Ding - Scientific Reports, 2023 - nature.com
Accumulating evidence shows that pseudogenes can function as microRNAs (miRNAs)
sponges and regulate gene expression. Mining potential interactions between pseudogenes …

[HTML][HTML] SPCMLMI: A structural perturbation-based matrix completion method to predict lncRNA–miRNA interactions

MN Wang, LL Lei, W He, DW Ding - Frontiers in Genetics, 2022 - frontiersin.org
Accumulating evidence indicated that the interaction between lncRNA and miRNA is crucial
for gene regulation, which can regulate gene transcription, further affecting the occurrence …