Clinical oncology can benefit substantially from imaging technologies that reveal
physiological characteristics with multiscale observations. Complementing conventional …

Photoacoustic imaging (or optoacoustic imaging) is an upcoming biomedical imaging
modality availing the benefits of optical resolution and acoustic depth of penetration. With its …

Biomedical photoacoustic tomography, which can provide high-resolution 3D soft tissue
images based on optical absorption, has advanced to the stage at which translation from the …

Abstract Machine learning has been developed dramatically and witnessed a lot of
applications in various fields over the past few years. This boom originated in 2009, when a …

Sonodynamic therapy (SDT) is noninvasive and possesses high body‐penetration depth,
showing great potential for the treatment of deep‐seated solid tumors. The efficacy of SDT …

In vivo quantitative assessment of oxyhaemoglobin saturation (sO2) status in tumour-
associated vessels could provide insights into cancer metabolism and behaviour. Here we …

Hypoxia has been shown to increase the aggressiveness and severity of tumor progression.
Along with chronic and acute hypoxic regions, solid tumors contain regions of cycling …

Breast cancer is one of the leading causes for cancer related deaths in women, and early
detection is extremely important to improve survival rates. Currently, x-ray mammogram is …

Functional imaging of microvascular dynamics in extremities delivers intuitive information for
early detection, diagnosis, and prognosis of vascular diseases. High-resolution and high …

Immunological tolerance induced by the hypoxic tumor microenvironment has been a major
challenge for current immune checkpoint blockade therapies. Here, a hypoxia‐responsive …