Trehalose and its applications in the food industry

A Chen, H Tapia, JM Goddard… - … Reviews in Food …, 2022 - Wiley Online Library
Trehalose is a nonreducing disaccharide composed of two glucose molecules linked by α, α‐
1, 1‐glycosidic bond. It is present in a wide variety of organisms, including bacteria, fungi …

Trehalose: current use and future applications

S Ohtake, YJ Wang - Journal of pharmaceutical sciences, 2011 - Elsevier
Trehalose, a disaccharide of glucose, has been reported to accumulate in many organisms
that can withstand extended periods of inanimation. Since this discovery, the properties of …

Trehalose: a review of properties, history of use and human tolerance, and results of multiple safety studies

AB Richards, S Krakowka, LB Dexter, H Schmid… - Food and chemical …, 2002 - Elsevier
This paper contains a review of the history, natural occurrence, human consumption,
metabolism, manufacture, and the results of eight standardized animal safety studies using …

Ecological significance of compatible solute accumulation by micro-organisms: from single cells to global climate

DT Welsh - FEMS microbiology reviews, 2000 - academic.oup.com
The osmoadaptation of most micro-organisms involves the accumulation of K+ ions and one
or more of a restricted range of low molecular mass organic solutes, collectively termed …

Insights on the evolution of trehalose biosynthesis

N Avonce, A Mendoza-Vargas, E Morett… - BMC evolutionary …, 2006 - Springer
Background The compatible solute trehalose is a non-reducing disaccharide, which
accumulates upon heat, cold or osmotic stress. It was commonly accepted that trehalose is …

Trehalose—the insect 'blood'sugar

SN Thompson - Advances in insect physiology, 2003 - books.google.com
Trehalose, the non-reducing disaccharide of glucose, is the principal sugar circulating in the
blood or haemolymph of most insects. Resistance to acid hydrolysis and an absence of …

Thermotolerance in Saccharomyces cerevisiae: the Yin and Yang of trehalose

MA Singer, S Lindquist - Trends in biotechnology, 1998 - cell.com
Trehalose, a sugar produced by a wide variety of organisms, has long been known for its
role in protecting certain organisms from desiccation. Recent work in yeast indicates that …

Alternative drying processes for the industrial preservation of lactic acid starter cultures

C Santivarangkna, U Kulozik… - Biotechnology progress, 2007 - Wiley Online Library
The preservation of lactic acid starter cultures by alternative drying processes has attracted
increasing attention due to the high costs and energy consumption of freezing and freeze …

Impact of product-related factors on immunogenicity of biotherapeutics

SK Singh - Journal of pharmaceutical sciences, 2011 - Elsevier
All protein therapeutics have the potential to be immunogenic. Several factors, including
patient characteristics, disease state, and the therapy itself, influence the generation of an …

[HTML][HTML] Innovative drying technologies for biopharmaceuticals

A Sharma, D Khamar, S Cullen, A Hayden… - International Journal of …, 2021 - Elsevier
In the past two decades, biopharmaceuticals have been a breakthrough in improving the
quality of lives of patients with various cancers, autoimmune, genetic disorders etc. With the …