Retro-miRs: novel and functional miRNAs originating from mRNA retrotransposition

RLV Mercuri, HB Conceição, GDA Guardia… - Mobile DNA, 2023 - Springer
Background Reverse-transcribed gene copies (retrocopies) have emerged as major sources
of evolutionary novelty. MicroRNAs (miRNAs) are small and highly conserved RNA …

Interplay between Tumor Mutational Burden and Mutational Profile and its effect on overall survival: a pilot study of metastatic patients treated with Immune Checkpoint …

CB Xavier, CDH Lopes, BM Awni, EF Campos… - Cancers, 2022 - mdpi.com
Simple Summary Recently, patients with high-TMB tumors received agnostic FDA approval
to be treated with pembrolizumab. However, some high-TMB patients do not show clinical …

Chemogenetic modulation of sensory neurons reveals their regulating role in melanoma progression

PAC Costa, WN Silva, PHDM Prazeres… - Acta neuropathologica …, 2021 - Springer
Sensory neurons have recently emerged as components of the tumor microenvironment.
Nevertheless, whether sensory neuronal activity is important for tumor progression remains …

Acute myeloid leukemia expresses a specific group of olfactory receptors

GDA Guardia, RG Naressi, VC Buzzato, JB da Costa… - Cancers, 2023 - mdpi.com
Simple Summary Acute myeloid leukemia (AML) is a type of cancer that affects blood cells
and is the most common type of acute leukemia in adults. Despite advances in treatment …

Approche à large échelle visant à détecter de nouveaux régulateurs de l'épissage alternatif au cours de la transition épithélio-mésenchymateuse.

JP Villemin - 2020 - theses.hal.science
L'épissage alternatif est l'un des mécanismes majeurs conduisant à la diversité du
protéome. Il est devenu très clair que ce mécanisme joue un rôle dans de nombreuses …