Highlights•Cytochrome P450 enzymes catalyse oxygen insertion into a wide range of
substrates.•Mutagenesis of P450s frequently allows novel substrate recognition.•P450s …

One approach to bringing enzymes together for multienzyme biocatalysis is genetic fusion.
This enables the production of multifunctional enzymes that can be used for whole‐cell …

The functionalization of terpenes using cytochrome P450 enzymes is a versatile route to the
production of useful derivatives that can be further converted to value-added products. Many …

Zearalenone (ZEA) is an estrogenic and ochratoxin A (OTA) is a hepatotoxic Fusarium
mycotoxin commonly seen in cereals and fruits products. No previous investigation has …

The growing preference for producing cytochrome P450-mediated natural products in
microbial systems stems from the challenging nature of the organic chemistry approaches …

Cytochrome P450 enzymes (CYPs) catalyze a series of C–H and C= C oxygenation
reactions, including hydroxylation, epoxidation, and ketonization. They are attractive …

Nitroaromatics are among the most important and commonly used chemicals but their
production often suffers from multiple unsolved challenges. We have previously described …

A variety of fusion proteins between the versatile redox partners flavodoxin (FldA) and
flavodoxin reductase (Fpr) from Escherichia coli was constructed with the aim to improve the …

Three different reductases have been fused to CYP153 monooxygenase from Marinobacter
aquaeolei. The most promising candidate has been analysed in terms of its linker part …

The direct hydroxylation of benzene to hydroquinone (HQ) under mild reaction conditions is
a challenging task for chemical catalysts. Cytochrome P450 (CYP) monooxygenases are …