New substituted benzimidazole derivatives: A patent review (2013–2014)

M Wang, X Han, Z Zhou - Expert opinion on therapeutic patents, 2015 - Taylor & Francis
Introduction: The benzimidazole nucleus is found in a variety of naturally occurring
compounds and is of significant importance in medicinal chemistry. Owing to its conspicuous …

An overview on biological evaluation of tetrazole derivatives

AK Kabi, S Sravani, R Gujjarappa, A Garg… - … : Basic Structures and …, 2022 - Springer
Tetrazoles are distinguished by a five-membered, doubly unsaturated ring which consists of
four nitrogen and one carbon atom with a molecular formula CN4H2, which have a wide …

Oral nanoemulsions of candesartan cilexetil: formulation, characterization and in vitro drug release studies

HH Ali, AA Hussein - Aaps Open, 2017 - Springer
Nanoemulsion is considered to be a new and exciting field of research that seeks to exploit
the attractive properties of components to improve oral delivery of drugs like candesartan …

Preparation and In vitro characterization of a novel self-nano emulsifying drug delivery system for a fixed-dose combination of candesartan cilexetil and …

MB Zewail, SA El-Gizawy, MA Osman… - Journal of Drug Delivery …, 2021 - Elsevier
A fixed-dose combination of Candesartan cilexetil (CAN) and Hydrochlorothiazide (HCTZ) is
commonly used for the management of hypertension. CAN (BCS class II) and HCTZ (BCS …

Effect of the structural modification of Candesartan with Zinc on hypertension and left ventricular hypertrophy

VR Martinez, AM Lima, N Stergiopulos… - European Journal of …, 2023 - Elsevier
Hypertension is the most common cause of left ventricular hypertrophy, contributing to heart
failure progression. Candesartan (Cand) is an angiotensin receptor antagonist widely used …

In silico drug repurposing studies for the discovery of novel Salicyl-AMP ligase (MbtA) Inhibitors

G Rakshit, A Biswas, V Jayaprakash - Pathogens, 2023 - mdpi.com
Tuberculosis (TB) continues to pose a global health challenge, exacerbated by the rise of
drug-resistant strains. The development of new TB therapies is an arduous and time …

Radioiodination and biological evaluation of candesartan as a tracer for cardiovascular disorder detection

MH Sanad, KM Sallam, FA Marzook… - Journal of Labelled …, 2016 - Wiley Online Library
The goal of the study aims to evaluate newly radioiodinated candesartan (CAN) as a
potential cardiovascular tracer. CAN was labeled using 125I with chloramine‐T (Ch‐T) and …

Oral solid self-nanoemulsifying drug delivery systems of candesartan citexetil: formulation, characterization and in vitro drug release studies

HH Ali, AA Hussein - AAPS Open, 2017 - Springer
Candesartan cilexetil is an ester prodrug antagonist to angiotensin II receptor type 1 (AT1)
used in management of many cardiovascular diseases. The absolute bioavailability of …

Design, optimization, and in vivo evaluation of invasome-mediated candesartan for the control of diabetes-associated atherosclerosis

AG Fouad, MRA Ali, DM Naguib, HO Farouk… - Drug Delivery and …, 2024 - Springer
Atherosclerosis is an inflammatory disease characterized by the accumulation of arterial
plaque. Diabetes mellitus stands out as a major risk factor for atherosclerosis. Candesartan …

Identifikasi Potensi Interaksi Obat Antihipertensi Pada Pasien Rawat Jalan di Rumah Sakit X Denpasar Periode Oktober-Desember 2021

D Oktianti, PPS Widyadewi… - … Pharmacy and Natural …, 2023 - ejournal.almaata.ac.id
Interaksi obat adalah sesuatu yang harus diperhatikan pada pasien yang mendapatkan
jenis obat dalam jumlah yang banyak. Hipertensi merupakan salah satu penyakit …