Production of functional eggs requires meiosis to be coordinated with developmental
signals. Oocytes arrest in prophase I to permit oocyte differentiation, and in most animals, a …

cAMP-dependent protein kinase is targeted to discrete subcellular locations by a family of
specific anchor proteins (A-kinase anchor proteins, AKAPs). Localization recruits protein …

Early embryonic development features rapid nuclear DNA replication cycles, but lacks mt
DNA replication. To meet the high‐energy demands of embryogenesis, mature oocytes are …

In the Drosophila ovary, hedgehog (hh) signaling from cells near the apical tip of the
germarium stimulates the proliferation and specification of somatic cells in region 2 of the …

The localization of Oskar at the posterior pole of the Drosophila oocyte induces the
assembly of the pole plasm and therefore defines where the abdomen and germ cells form …

During oogenesis, oocytes arrest at meiotic prophase I to acquire competencies for
resuming meiosis, fertilization, and early embryonic development. Following this arrested …

Collective cell movement is a mechanism for invasion identified in many developmental
events. Examples include the movement of lateral-line neurons in Zebrafish, cells in the …

▪ Abstract The Drosophila ovary provides a favorable model system in which to study cellular
morphogenesis. The development of a mature egg involves a syncytium of 16 germline cells …

We identified a unique type II cAMP-dependent protein kinase regulatory subunit (PKA-RII)
gene in Drosophila melanogaster and a severely hypomorphic if not null mutation, pka-RII …

The primitive gonad of the Drosophila embryo is formed from two cell types, the somatic
gonad precursor cells (SGPs) and the germ cells, which originate at distant sites. To reach …