[HTML][HTML] Objectives, design and main findings until 2020 from the Rotterdam Study
MA Ikram, G Brusselle, M Ghanbari… - European journal of …, 2020 - Springer
Abstract The Rotterdam Study is an ongoing prospective cohort study that started in 1990 in
the city of Rotterdam, The Netherlands. The study aims to unravel etiology, preclinical …
the city of Rotterdam, The Netherlands. The study aims to unravel etiology, preclinical …
[HTML][HTML] The Rotterdam Study: 2018 update on objectives, design and main results
MA Ikram, GGO Brusselle, SD Murad… - European journal of …, 2017 - Springer
Abstract The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of
Rotterdam in The Netherlands. The study targets cardiovascular, endocrine, hepatic …
Rotterdam in The Netherlands. The study targets cardiovascular, endocrine, hepatic …
Precision medicine in antidepressants treatment
EE Tsermpini, A Serretti, V Dolžan - Precision Medicine, 2023 - Springer
Precision medicine uses innovative approaches to improve disease prevention and
treatment outcomes by taking into account people's genetic backgrounds, environments …
treatment outcomes by taking into account people's genetic backgrounds, environments …
[HTML][HTML] Role of pharmacokinetics and pharmacogenetics of antidepressant-induced prolongation of the QT interval and Torsade de Pointes in patients with mental …
NA Shnayder, AV Kidyaeva, EE Vaiman… - Personalized Psychiatry …, 2023 - jppn.ru
Antidepressants (ADs) include drugs of various pharmacological groups, which are mainly
used for the treatment of mental disorders (major depressive disorder, obsessive …
used for the treatment of mental disorders (major depressive disorder, obsessive …
A large genome-wide association study of QT interval length utilizing electronic health records
TJ Hoffmann, M Lu, A Oni-Orisan, C Lee, N Risch… - Genetics, 2022 - academic.oup.com
QT interval length is an important risk factor for adverse cardiovascular outcomes; however,
the genetic architecture of QT interval remains incompletely understood. We conducted a …
the genetic architecture of QT interval remains incompletely understood. We conducted a …
Genetic predisposition to bevacizumab-induced hypertension
Objective Bevacizumab, a monoclonal antibody to VEGF, has shown efficacy in ovarian,
cervical and endometrial cancer in addition to several other solid tumors. Serious side …
cervical and endometrial cancer in addition to several other solid tumors. Serious side …
DNA Methylation Predicts Adverse Outcomes of Coronary Artery Disease
M Qin, Q Wu, X Tian, Q Zhu, X Fang, X Chen, C Liu… - medRxiv, 2023 - medrxiv.org
Background Adverse outcomes including myocardial infarction and stroke render coronary
artery disease (CAD) a leading cause of death worldwide. Biomarkers that predict such …
artery disease (CAD) a leading cause of death worldwide. Biomarkers that predict such …
A critical appraisal of pharmacogenetic inference
RAJ Smit, R Noordam, S Le Cessie, S Trompet… - Clinical …, 2018 - Wiley Online Library
In essence, pharmacogenetic research is aimed at discovering variants of importance to
gene‐treatment interaction. However, epidemiological studies are rarely set up with this goal …
gene‐treatment interaction. However, epidemiological studies are rarely set up with this goal …
[PDF][PDF] Молекулярно-генетические аспекты лекарственно-индуцированного синдрома удлиненного интервала QT
ЛВ Колоцей, ВА Снежицкий - Кардиология в Беларуси, 2021 - academia.edu
Синдром удлиненного интервала QT (СУИ QT) может быть как врожденным, так и
приобретенным, причем последний наиболее часто вызывается воздействием …
приобретенным, причем последний наиболее часто вызывается воздействием …
[HTML][HTML] Genomic approaches for the elucidation of genes and gene networks underlying cardiovascular traits
ME Adriaens, CR Bezzina - Biophysical reviews, 2018 - Springer
Genome-wide association studies have shed light on the association between natural
genetic variation and cardiovascular traits. However, linking a cardiovascular trait …
genetic variation and cardiovascular traits. However, linking a cardiovascular trait …