Chronic low-grade inflammation in adipose tissue (AT) is a hallmark of obesity and
contributes to various metabolic disorders, such as type 2 diabetes and cardiovascular …

Adiponectin (a protein consisting of 244 amino acids and characterized by a molecular
weight of 28 kDa) is a cytokine that is secreted from adipose tissues (adipokine). Available …

Introduction: Recent observations have shown that lengthening the daily eating period may
contribute to the onset of chronic diseases. Time-restricted eating (TRE) is a diet that …

Adiponectin is an adipocyte-specific factor, first described in 1995. Over the past two
decades, numerous studies have elucidated the physiological functions of adiponectin in …

Exosomes/small extracellular vesicles (sEVs) can serve as multifactorial mediators of cell-to-
cell communication through their miRNA and protein cargo. Quantitative proteomic analysis …

Adiponectin, first described in the mid-1990s, is one of the most widely studied adipokines to
date. Studies of its regulation, biogenesis and physiological effects have yielded great …

Obesity-linked type 2 diabetes is one of the paramount causes of morbidity and mortality
worldwide, posing a major threat on human health, productivity, and quality of life. Despite …

Adipose tissue plays a central role in regulating whole-body energy and glucose
homeostasis through its subtle functions at both organ and systemic levels. On one hand …

Improving physical function and mobility in a continuously expanding elderly population
emerges as a high priority of medicine today. Muscle mass, strength/power, and maximal …

Adipose tissue is now recognized as an important endocrine organ, capable of secreting a
large number of endocrine factors which regulate a wide variety of physiological functions …