The impact of tonic GABAA receptor-mediated inhibition on neuronal excitability varies across brain region and cell type
V Lee, J Maguire - Frontiers in neural circuits, 2014 - frontiersin.org
The diversity of GABAA receptor (GABAAR) subunits and the numerous configurations
during subunit assembly give rise to a variety of receptors with different functional properties …
during subunit assembly give rise to a variety of receptors with different functional properties …
Depolarising and Hyperpolarising Actions of GABAA Receptor Activation on Gonadotrophin‐Releasing Hormone Neurones: Towards an Emerging Consensus
AE Herbison, SM Moenter - Journal of neuroendocrinology, 2011 - Wiley Online Library
The gonadotrophin‐releasing hormone (GnRH) neurones represent the final output
neurones of a complex neuronal network that controls fertility. It is now appreciated that …
neurones of a complex neuronal network that controls fertility. It is now appreciated that …
The role of GABA in the regulation of GnRH neurons
M Watanabe, A Fukuda, J Nabekura - Frontiers in neuroscience, 2014 - frontiersin.org
Gonadotropin-releasing hormone (GnRH) neurons form the final common pathway for the
central regulation of reproduction. Gamma-amino butyric acid (GABA) has long been …
central regulation of reproduction. Gamma-amino butyric acid (GABA) has long been …
A functional role for both γ‐aminobutyric acid (GABA) transporter‐1 and GABA transporter‐3 in the modulation of extracellular GABA and GABAergic tonic …
F Kersanté, SCS Rowley, I Pavlov… - The Journal of …, 2013 - Wiley Online Library
Key points• The extracellular concentration of the neurotransmitter γ‐aminobutyric acid
(GABA) is critical in determining GABAA receptor‐mediated tonic conductance in the …
(GABA) is critical in determining GABAA receptor‐mediated tonic conductance in the …
Modulation of gonadotropin-releasing hormone neuron activity and secretion in mice by non-peptide neurotransmitters, gasotransmitters, and gliotransmitters
DJ Spergel - Frontiers in endocrinology, 2019 - frontiersin.org
Gonadotropin-releasing hormone (GnRH) neuron activity and GnRH secretion are essential
for fertility in mammals. Here, I review findings from mouse studies on the direct modulation …
for fertility in mammals. Here, I review findings from mouse studies on the direct modulation …
GABAergic regulation of the HPA and HPG axes and the impact of stress on reproductive function
The hypothalamic–pituitary–adrenal (HPA) and hypothalamic–pituitary–gonadal (HPG) axes
are regulated by GABAergic signaling at the level of corticotropin-releasing hormone (CRH) …
are regulated by GABAergic signaling at the level of corticotropin-releasing hormone (CRH) …
Glucagon-like peptide-1 excites firing and increases GABAergic miniature postsynaptic currents (mPSCs) in gonadotropin-releasing hormone (GnRH) neurons of the …
I Farkas, C Vastagh, E Farkas, F Bálint… - Frontiers in cellular …, 2016 - frontiersin.org
Glucagon-like peptide-1 (GLP-1), a metabolic signal molecule, regulates reproduction,
although, the involved molecular mechanisms have not been elucidated, yet. Therefore …
although, the involved molecular mechanisms have not been elucidated, yet. Therefore …
Delayed neuroendocrine sexual maturation in female rats after a very low dose of bisphenol A through altered GABAergic neurotransmission and opposing effects of a …
D Franssen, A Gérard, B Hennuy, AF Donneau… - …, 2016 - academic.oup.com
Rat sexual maturation is preceded by a reduction of the interpulse interval (IPI) of GnRH
neurosecretion. This work aims at studying disruption of that neuroendocrine event in …
neurosecretion. This work aims at studying disruption of that neuroendocrine event in …
Hypothalamic GABRA5-positive neurons control obesity via astrocytic GABA
The lateral hypothalamic area (LHA) regulates food intake and energy balance. Although
LHA neurons innervate adipose tissues, the identity of neurons that regulate fat is undefined …
LHA neurons innervate adipose tissues, the identity of neurons that regulate fat is undefined …
In vivo recordings of GnRH neuron firing reveal heterogeneity and dependence upon GABAA receptor signaling
S Constantin, KJ Iremonger… - Journal of …, 2013 - Soc Neuroscience
The gonadotropin-releasing hormone (GnRH) neurons are the key cells regulating fertility in
all mammalian species. The scattered distribution of these neurons has made investigation …
all mammalian species. The scattered distribution of these neurons has made investigation …