Reproductive Aging in Caenorhabditis elegans: From Molecules to Ecology

A Scharf, F Pohl, BM Egan, Z Kocsisova… - Frontiers in cell and …, 2021 - frontiersin.org
Aging animals display a broad range of progressive degenerative changes, and one of the
most fascinating is the decline of female reproductive function. In the model organism …

The use of plant growth-promoting bacteria to prevent nematode damage to plants

E Gamalero, BR Glick - Biology, 2020 - mdpi.com
Simple Summary It has been estimated that 100 g of bulk soil can host about 2000–4000
nematodes and this amount is increased 5-fold in the rhizosphere. A certain number of these …

[HTML][HTML] Exposure to polystyrene nanoparticles at predicted environmental concentrations enhances toxic effects of Acinetobacter johnsonii AC15 infection on …

M Tang, G Ding, L Li, G Xiao, D Wang - Ecotoxicology and Environmental …, 2023 - Elsevier
Nanoplastics and microbial pathogens are both widely distributed in the environment;
however, their combined toxicity remains largely unclear. Using Caenorhabditis elegans as …

Pathogenic bacteria modulate pheromone response to promote mating

T Wu, M Ge, M Wu, F Duan, J Liang, M Chen… - Nature, 2023 - nature.com
Pathogens generate ubiquitous selective pressures and host–pathogen interactions alter
social behaviours in many animals,,–. However, very little is known about the neuronal …

Diverse states and stimuli tune olfactory receptor expression levels to modulate food-seeking behavior

IG McLachlan, TS Kramer, M Dua, EM DiLoreto… - Elife, 2022 - elifesciences.org
Animals must weigh competing needs and states to generate adaptive behavioral
responses to the environment. Sensorimotor circuits are thus tasked with integrating diverse …

Dynamic functional connectivity in the static connectome of Caenorhabditis elegans

SW Flavell, A Gordus - Current opinion in neurobiology, 2022 - Elsevier
A hallmark of adaptive behavior is the ability to flexibly respond to sensory cues. To
understand how neural circuits implement this flexibility, it is critical to resolve how a static …

Understanding the factors regulating host–microbiome interactions using Caenorhabditis elegans

A Singh, RJ Luallen - Philosophical Transactions of the …, 2024 - royalsocietypublishing.org
The Human Microbiome Project was a research programme that successfully identified
associations between microbial species and healthy or diseased individuals. However, a …

Neuroendocrine gene expression coupling of interoceptive bacterial food cues to foraging behavior of C. elegans

SA Boor, JD Meisel, DH Kim - Elife, 2024 - elifesciences.org
Animal internal state is modulated by nutrient intake, resulting in behavioral responses to
changing food conditions. The neural mechanisms by which internal states are generated …

Effector and regulator: Diverse functions of C. elegans C-type lectin-like domain proteins

B Pees, W Yang, A Kloock, C Petersen, L Peters… - PLoS …, 2021 - journals.plos.org
In C. elegans, 283 clec genes encode a highly diverse family of C-type lectin-like domain
(CTLD) proteins. Since vertebrate CTLD proteins have characterized functions in defense …

The neuroimmune CGRP–RAMP1 axis tunes cutaneous adaptive immunity to the microbiota

W Kulalert, AC Wells, VM Link, AI Lim… - Proceedings of the …, 2024 - National Acad Sciences
The somatosensory nervous system surveils external stimuli at barrier tissues, regulating
innate immune cells under infection and inflammation. The roles of sensory neurons in …