Regeneration is the process of replacing/restoring a damaged cell/tissue/organ to its full
function and is limited respecting complexity of specific organ structures and the level of …

The mitogen-activated protein kinase (MAPK) signaling pathway is the primary regulatory
module of various cellular processes such as cell proliferation, differentiation, and stress …

Mitogen-activated protein (MAP) kinases are a central component in signaling networks in a
multitude of mammalian cell types. This review covers recent advances on specific functions …

A formidable challenge in neural repair in the adult central nervous system (CNS) is the long
distances that regenerating axons often need to travel in order to reconnect with their …

The assembly of a new growth cone is a prerequisite for axon regeneration after injury.
Creation of a new growth cone involves multiple processes, including calcium signalling …

The expansion of the neocortex during mammalian brain evolution results primarily from an
increase in neural progenitor cell divisions in its two principal germinal zones during …

In contrast to neurons in the central nervous system, mature neurons in the mammalian
peripheral nervous system (PNS) can regenerate axons after injury, in part, by enhancing …

Hydra's almost unlimited regenerative potential is based on Wnt signaling, but so far it is
unknown how the injury stimulus is transmitted to discrete patterning fates in head and foot …

Axons actively self-destruct following genetic, mechanical, metabolic, and toxic insults, but
the mechanism of axonal degeneration is poorly understood. The JNK pathway promotes …

The ability of injured axons to regenerate declines with age, yet the mechanisms that
regulate axon regeneration in response to age are not known. Here we show that axon …