In December 1983, a seminal paper appeared on the overexpression of human IFN-β in
insect cells with a genetically engineered baculovirus. The finding that baculoviruses …

The baculovirus‐insect cell expression system is widely used in producing recombinant
proteins. This review is focused on the use of this expression system in developing …

The number of approved biopharmaceuticals, where product quality attributes remain of
major importance, is increasing steadily. Within the available variety of expression hosts, the …

Over the past two decades, baculoviruses have become workhorse research tools for
transient transgene expression. Although they have not yet been used directly as a gene …

Viral vectors are an emerging, exciting class of biologics whose application in vaccines,
oncology, and gene therapy has grown exponentially in recent years. Following first …

Baculoviruses are arthropod-specific, enveloped viruses with circular, supercoiled double-
stranded deoxyribonucleic acid genomes. While many viruses are studied to seek solutions …

Over 90% of pathogens of medical importance invade the organism through mucosal
surfaces, which makes it urgent to develop safe and effective mucosal vaccines and …

To enhance the production efficiency of foreign protein in baculovirus expression systems,
the effects of polyhedrin fragments were investigated by fusion expressing them with the …

Baculoviruses have proven capacity for the production of recombinant proteins including
virus-like particles and as viral vectors. Recent progress in preclinical studies suggest that …

Vaccination of animals has been carried out for centuries, and it is the most cost-effective
and sustainable method of controlling infectious diseases. Veterinary vaccines not only are …