Background Increased peripheral inflammation has been consistently reported in patients
with major depressive disorder (MDD). However, only few studies have explored markers of …

As the professional phagocytes of the brain, microglia orchestrate the immunological
response and play an increasingly important role in maintaining homeostatic brain functions …

Bipolar disorder (BD) is a chronic affective disorder with extreme mood swings that include
mania or hypomania and depression. Though the exact mechanism of BD is unknown …

Schizophrenia and bipolar disorder are disabling psychiatric disorders with a worldwide
prevalence of approximately 1%. Both disorders present chronic and deteriorating …

The overlapping symptoms of behavioural variant frontotemporal dementia (bvFTD) and
primary psychiatric disorders (such as depressive disorder, schizophrenia spectrum, and …

Psychiatric disorders represent a great medical and social challenge and people suffering
from these conditions face many impairments regarding personal and professional life. In …

Bipolar disorder (BD) is characterized by mood changes, including recurrent manic,
hypomanic, and depressive episodes, which may involve mixed symptoms. Despite the …

Findings from epidemiological studies, biomarker measurements and animal experiments
suggest a role for aberrant immune processes in the pathogenesis of major depressive …

There have been a large number of reports about glial cell dysfunction being related to
major psychiatric diseases such as schizophrenia (SCZ), bipolar disorder (BD), and major …

Different regions of the cortex have been implicated in the pathophysiology of
schizophrenia. Recently published data suggested there are many more changes in gene …