Role of nuclear progesterone receptor isoforms in uterine pathophysiology

B Patel, S Elguero, S Thakore… - Human reproduction …, 2015 - academic.oup.com
BACKGROUND Progesterone is a key hormonal regulator of the female reproductive
system. It plays a major role to prepare the uterus for implantation and in the establishment …

Implications of the polymorphism of HLA-G on its function, regulation, evolution and disease association

EA Donadi, EC Castelli, A Arnaiz-Villena… - Cellular and molecular …, 2011 - Springer
The HLA-G gene displays several peculiarities that are distinct from those of classical HLA
class I genes. The unique structure of the HLA-G molecule permits a restricted peptide …

HLA-G: from biology to clinical benefits

ED Carosella, P Moreau, J LeMaoult… - Trends in …, 2008 - cell.com
The relevance of the nonclassical human leukocyte antigen (HLA) class I molecule HLA-G in
human physiological and pathological contexts has been the center of intense investigation …

Progesterone receptors, their isoforms and progesterone regulated transcription

BM Jacobsen, KB Horwitz - Molecular and cellular endocrinology, 2012 - Elsevier
This review discusses mechanisms by which progesterone receptors (PR) regulate
transcription. We examine available data in different species and tissues regarding:(1) …

Progesterone during pregnancy: endocrine–immune cross talk in mammalian species and the role of stress

P Arck, PJ Hansen, B Mulac Jericevic… - American journal of …, 2007 - Wiley Online Library
Progesterone is critical for the establishment and the maintenance of pregnancy, both by its
endocrine and immunological effects. The genomic actions of progesterone are mediated by …

The immunosuppressive molecule HLA-G and its clinical implications

Á González, V Rebmann, J LeMaoult… - Critical reviews in …, 2012 - Taylor & Francis
Human leukocyte antigen G (HLA-G) is a non-classical major histocompatibility complex
(MHC) class I molecule that, through interaction with its receptors, exerts important …

Transcriptional and Posttranscriptional Regulations of the HLA-G Gene

EC Castelli, LC Veiga-Castelli, L Yaghi… - Journal of …, 2014 - Wiley Online Library
HLA-G has a relevant role in immune response regulation. The overall structure of the HLA-
G coding region has been maintained during the evolution process, in which most of its …

Natural killer cells in recurrent miscarriage: An overview

B Guerrero, F Hassouneh, E Delgado… - Journal of Reproductive …, 2020 - Elsevier
Recurrent Miscarriage is an early pregnancy complication which affects about 1–3% of child-
bearing couples. The mechanisms involved in the occurrence of recurrent miscarriages are …

Insights into HLA-G Genetics Provided by Worldwide Haplotype Diversity

EC Castelli, J Ramalho, IOP Porto, THA Lima… - Frontiers in …, 2014 - frontiersin.org
Human leukocyte antigen G (HLA-G) belongs to the family of non-classical HLA class I
genes, located within the major histocompatibility complex (MHC). HLA-G has been the …

A Comprehensive Study of Polymorphic Sites along the HLA-G Gene: Implication for Gene Regulation and Evolution

EC Castelli, CT Mendes-Junior… - Molecular biology …, 2011 - academic.oup.com
HLA-G molecule plays an important role on immune response regulation and has been
implicated on the inhibition of T and natural killer cell cytolytic function and inhibition of …