Priming approaches to improve the efficacy of mesenchymal stromal cell-based therapies
NC Noronha, A Mizukami, C Caliári-Oliveira… - Stem cell research & …, 2019 - Springer
Multipotent mesenchymal stromal cells (MSC) have been widely explored for cell-based
therapy of immune-mediated, inflammatory, and degenerative diseases, due to their …
therapy of immune-mediated, inflammatory, and degenerative diseases, due to their …
Additive manufacturing of porous magnesium alloys for biodegradable orthopedic implants: Process, design, and modification
Biodegradable magnesium (Mg) alloys exhibit excellent biocompatibility, adequate
mechanical properties, and osteogenic effect. They can contribute to complete recovery of …
mechanical properties, and osteogenic effect. They can contribute to complete recovery of …
Mesenchymal stem cell perspective: cell biology to clinical progress
MF Pittenger, DE Discher, BM Péault… - NPJ Regenerative …, 2019 - nature.com
The terms MSC and MSCs have become the preferred acronym to describe a cell and a cell
population of multipotential stem/progenitor cells commonly referred to as mesenchymal …
population of multipotential stem/progenitor cells commonly referred to as mesenchymal …
Biological functions of mesenchymal stem cells and clinical implications
Mesenchymal stem cells (MSCs) are isolated from multiple biological tissues—adult bone
marrow and adipose tissues and neonatal tissues such as umbilical cord and placenta. In …
marrow and adipose tissues and neonatal tissues such as umbilical cord and placenta. In …
Mesenchymal stem cell secretome: toward cell-free therapeutic strategies in regenerative medicine
FJ Vizoso, N Eiro, S Cid, J Schneider… - International journal of …, 2017 - mdpi.com
Earlier research primarily attributed the effects of mesenchymal stem cell (MSC) therapies to
their capacity for local engrafting and differentiating into multiple tissue types. However …
their capacity for local engrafting and differentiating into multiple tissue types. However …
Potential pre-activation strategies for improving therapeutic efficacy of mesenchymal stem cells: current status and future prospects
M Li, Y Jiang, Q Hou, Y Zhao, L Zhong, X Fu - Stem cell research & …, 2022 - Springer
Mesenchymal stem cell (MSC)-based therapy has been considered as a promising
approach targeting a variety of intractable diseases due to remarkable multiple effect of …
approach targeting a variety of intractable diseases due to remarkable multiple effect of …
Senescence in human mesenchymal stem cells: functional changes and implications in stem cell-based therapy
V Turinetto, E Vitale, C Giachino - International journal of molecular …, 2016 - mdpi.com
Regenerative medicine is extensively interested in developing cell therapies using
mesenchymal stem cells (MSCs), with applications to several aging-associated diseases …
mesenchymal stem cells (MSCs), with applications to several aging-associated diseases …
Scaffold-free cell-based tissue engineering therapies: advances, shortfalls and forecast
Cell-based scaffold-free therapies seek to develop in vitro organotypic three-dimensional
(3D) tissue-like surrogates, capitalising upon the inherent capacity of cells to create tissues …
(3D) tissue-like surrogates, capitalising upon the inherent capacity of cells to create tissues …
Defining physiological normoxia for improved translation of cell physiology to animal models and humans
TP Keeley, GE Mann - Physiological reviews, 2019 - journals.physiology.org
The extensive oxygen gradient between the air we breathe (Po2~ 21 kPa) and its ultimate
distribution within mitochondria (as low as~ 0.5–1 kPa) is testament to the efforts expended …
distribution within mitochondria (as low as~ 0.5–1 kPa) is testament to the efforts expended …
[HTML][HTML] Oxygen in stem cell biology: a critical component of the stem cell niche
The defining hallmark of stem cells is their ability to self-renew and maintain multipotency.
This capacity depends on the balance of complex signals in their microenvironment. Low …
This capacity depends on the balance of complex signals in their microenvironment. Low …